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Showing 1 to 3 of 3 for “"Pressurized Carbon Dioxide"”.
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Feasibility of AquasolveTM HPMC-AS Lg via Hot-melt Extrusion: Effect of Pressurized CO2 on Physico-mechanical Properties
… hot-melt extrusion, and to examine the effect of pressurized carbon dioxide (P-CO2) on the physico-mechanical properties of Efavirenz (EFA)-loaded extrudates (EXT). EFA is as a poorly water-soluble drug and HPMC-AS LG was chosen as a carrier for this study. To optimize the process parameters and …
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Influence of novel techniques on solubility, mechanical properties and permeability via hot melt extrusion technology
… research project was to study the effect of pressurized carbon dioxide (P-CO2) on the physico-mechanical properties of three different grades of cellulose polymers, Klucel™ ELF, EF and LF hydroxypropylcellulose (HPC) resulting from hot melt extrusion techniques, and to assess the …
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Development and Characterization of Sustained-Release Formulations via Novel Hot Melt Extrusion Techniques
… Part of this research project focus on injecting pressurized carbon dioxide (P-CO2) gas during the HME process. These combined techniques have an additional advantage of being adaptable and portable to a hot melt extruder instrument. The use of HME alongside with other techniques (P-CO2 or co …