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Showing 1 to 3 of 3 for “"Preptin"”.
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Purification of Recombinant HIS6-GFP-Preptin Fusion Protiens
<p>Preptin, a 34-amino-acid peptide derived from proinsulin-like growth factor II, has emerged as a promising therapeutic candidate for both Type 2 diabetes mellitus and osteoporosis. Its dual functionality—stimulating insulin secretion without inducing hypoglycemia and promoting osteoblast …
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Design, Cloning, and Expression of Rat Preptin and Alanine Analogs
… employed to determine the structural epitopes of preptin; a newly discovered polypeptide found on the proinsulin-like growth factor II. The alanine scanning mutagenesis was accomplished by the use of, cloning, affinity chromatography, gel electrophoresis, gene sequencing, and mass spectra. …
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Recombinant Expression of Preptin Analogs for Alanine Scanning Mutagenesis of Residues 27-29
<p>The novel peptide preptin consists of 34 amino acid residues corresponding to Asp<sup>69</sup>-Leu<sup>102</sup> of proinsulin-like growth factor E-peptide. Preptin has been isolated from pancreatic beta cells, and it has been found to exhibit both metabolic and mitogenic activities. This makes …