Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Prenatal Ethanol Exposure"”.
-
Chronic prenatal ethanol exposure produces neurobehavioural and metabolic dysfunction in guinea pig offspring
Maternal ethanol consumption during pregnancy can produce teratogenic outcomes in offspring, which are collectively termed Fetal Alcohol Spectrum Disorder (FASD). Central nervous system (CNS) dysfunction is a debilitating and permanent manifestation of FASD. Recent studies indicate that chronic …
-
A novel low-density lipoprotein receptor-related protein protects against environmental teratogens
… between genetic and environmental factors. Prenatal ethanol exposure results in the highest number of preventable birth defects in the United States. Prenatal ethanol exposure interacts with another well-established teratogen: prenatal hyperthermia. Additionally, each of these teratogens …
-
The effects of prenatal and early-postnatal ethanol exposure on rat brain neurochemistry and behaviour
… and behavioural deficits observed after exposure to alcohol in utero, is a major public health issue specifically in South Africa. South Africa is thought to have the highest prevalence of FASD in the world. FASD presents as a variety of learning and memory deficits as well as …
-
Biochemical changes in animal models of fetal alcohol spectrum disorder
… (Roozen, 2016). FASD is caused by maternal ethanol intake during pregnancy. However, recommendations of the amounts of alcohol safe to drink during pregnancy are not established. Further, we lack a comprehensive understanding of the biochemical pathways modified in prenatal ethanol exposure. …
-
Moderate Ethanol Consumption by the Pregnant Guinea Pig Increases Ethanol Preference in Offspring
Ethanol teratogenicity involving the developing brain is the leading preventable cause of mental deficiency in the Western world. Chronic prenatal ethanol exposure (CPEE) may be a risk factor for ethanol abuse and altered responsiveness to nicotine in postnatal life. Previous studies in our …
-
Role of testosterone in mediating prenatel ethanol effects on hypothalamic-pituitary-adrenal activity in male rats
Prenatal ethanol (E) exposure has marked effects on development of the hypothalamic-pituitary-adrenal (HPA) and -gonadal (HPG) axes. E rats show HPA hyperresponsiveness to stressors and altered reproductive function in adulthood. Importantly, prenatal ethanol differentially alters stress …
-
Neuroprotectant Properties of Neurosteroids During Neonatal Ethanol Exposure
<p>Neonatal ethanol exposure significantly affected development of medial prefrontal cortex pyramidal neurons by decreasing apical dendritic length and intersections. Neurosteroid treatment affected neuronal measurements in a sex-dependent manner, with neurosteroids having minimal to no effect on …