Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Pregabalin"”.
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The trends and rates of gabapentin and pregabalin
… prescribing rates and trends of gabapentin and pregabalin is limited. Identifying the prescribing rates and trends of gabapentinoids will help us to quantify the scale of the issue and allow us to examine whether there are associations with demographic factors and subsequent health …
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Gabapentinoids for treatment of neuropathic pain: a medicines usage evaluation at the Groote Schuur hospital chronic pain management clinic
… system, affects 6.9 – 10 % of people worldwide. Pregabalin is currently recommended as a first line drug for NP in South Africa. Methods A cross-sectional retrospective descriptive medicines usage evaluation (MUE) of Pregabalin at Groote Schuur Chronic Pain clinic for the year 2017 was conducted. …
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The newer anticonvulsants in the treatment of generalised anxiety disorder: a systematic review and meta-analysis
… lamotrigine, levetiracetam, oxcarbazepine, pregabalin, tiagabine, topiramate and zonisamide) were investigated as they were considered to have a more benign side effect profile and fewer drug interactions than older anticonvulsants. This study is a systematic review and meta-analysis of the …
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The Effect of a Novel Multimodal Therapeutic Protocol on Patient Reported Post-Neurosurgical Pain Scores, versus the Current Postoperative Analgesic Practice Employed at a Local South African Hospital – An Investigator Initiated Randomized Controlled Trial
… The experimental group received oral 150mg pregabalin one hour before surgery, IV 40mg parecoxib at surgical closure, and oral 150mg pregabalin two hours after surgery. The control group received a matching placebo at these respective time points. Postoperatively, all patients received …
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Factors associated with co-prescription of opioids and gabapentinoids
<b>Background</b>: gabapentin and pregabalin are commonly used for relieving neuropathic pain, but also could lead to diversion, dependence and tolerance, with adverse effects on the central nervous system, especially when co-prescribed with opioids. The rates of prescribing gabapentinoids have …
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Development of Multiple Microemulsion Eye Drops for Sustained Release of New Glaucoma Drug
… as a novel modulator of IOP and confirmed that pregabalin targeted CACNA2D1 in eye tissues (ciliary body and trabecular meshwork) to lower IOP in a dose-dependent manner. The research presented in this dissertation aimed to develop a once-daily ocular pregabalin-loaded multiple …
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Discriminative Stimulus Effects of Gabapentin
… Pentobarbital produced full substitution, while pregabalin, carbamazepine, fentanyl, and buspirone produced partial substitution (≥ 60% gabapentin-lever responding) for gabapentin. Ethanol and raclopride did not substitute for gabapentin. The psychostimulant amphetamine did not produce …
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Use and misuse of sedative drugs and related substances - Findings in the general population and in individuals with opioid dependence
… between prescriptions of ‘z-drug’ hypnotics and pregabalin and overdose death. Conclusions: It is important to be aware of the associations with mental health problems and quality of life in individuals with sedative misuse. In individuals with opioid dependence, clinicians also need to be aware …
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Eficacia de los gabapentinoides para disminuir la intensidad del dolor en la neuropatía dolorosa de los pacientes adultos que conviven con VIH. Revisión sistemática de literatura
… manejo del dolor neuropático con gabapentina o pregabalina, sin embargo solo se logró realizar análisis estadístico del desenlace primario en 3 de ellos. Resultados y conclusión: Hay significancia estadística en 2 de los 3 estudios cuándo se evalúa la mejoría del dolor en la neuropatía dolorosa …