Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Precocious puberty"”.
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Association of aromatase (TTTA)n repeat polymorphisms with central precocious puberty in girls.
Objective: Precocious puberty is characterized by early activation of the pituitary gonadal axis. Estrogen is the final key factor to start onset of puberty. The cytochrome P450 19A1 (CYP19A1) gene encodes an aromatase that is responsible for the conversion of androgens to estrogen, which is key …
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The Mutation Analysis of GnRH1 and GnRH Receptor Gene in Korean Girls woth Central Precocious Puberty
"차 례 국문요약 i 차례 iii 그림차례 v 표차례 vi 약어 vii I. 서론 1 II. 대상 및 방법 5 A. 대상 환자군의 선별과 Genomic DNA 준비 5 1. 대상 환자군과 대조군 5 2. 성선자극호르몬방출호르몬 자극 검사 5 3. 환자군과 대조군으로부터 채혈 5 4. Genomic DNA 추출 6 B. GnRH1 와 GnRH-R 유전자 돌연변이 분석 6 1. GnRH1 유전자의 돌연변이 분석 6 2. GnRH-R 유전자의 돌연변이 분석 7 C. GnRH1 와 GnRH-R 유전자의 단일염기다형성 유전자형 분석 7 …
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Changes in BMD and Body Composition in Children with Central Precocious Puberty Before and After Treatment with GnRH Agonist
… composition in 121 Korean girls with central precocious puberty (CPP) before, during, and after 1 year of treatment with gonadotropin-releasing hormone (GnRH) agonist. BMD, bone mineral content (BMC), lean body mass (LBM), and fat mass (FM) were measured at baseline and after 1 year of …
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CAPITALISM, CONTRACEPTION AND CHEMICALS: A MEDICAL ANTHROPOLOGICAL ANALYSIS OF THE PREMATURE SEXUAL DEVELOPMENT EPIDEMIC IN PUERTO RICAN FEMALES
… of the world’s highest recorded prevalence of precocious puberty and premature thelarche that occurred in Puerto Rico in the late 1970s. After 30 years of biomedical research, definite etiologies of this epidemic remain unknown; prompting for a more dynamic, biosocial approach in studying this …
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CAPITALISM, CONTRACEPTION AND CHEMICALS: A MEDICAL ANTHROPOLOGICAL ANALYSIS OF THE PREMATURE SEXUAL DEVELOPMENT EPIDEMIC IN PUERTO RICAN FEMALES
… of the world’s highest recorded prevalence of precocious puberty and premature thelarche that occurred in Puerto Rico in the late 1970s. After 30 years of biomedical research, definite etiologies of this epidemic remain unknown; prompting for a more dynamic, biosocial approach in studying this …
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Effects of the Antiandrogen Cyproterone Acetate on Maturing Male Mice.
… and Barreca, 1977), diseases of the prostate, precocious puberty (Gräf et al., 1974), male contraception (Hammerstein, 1977) and the treatment of male sex offenders (Jeffcoate et al., 1980). Additionally, they have been used as a tool to examine certain androgen-dependent processes, of which …
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GnRH and neuropeptide regulation of gonadotropin secretion from cultured human pituitary cells
… of endocrine disorders, such as endometriosis, precocious puberty, infertility and prostatic cancer. Selection of these analogues for clinical use have been previously based on their activities in animal models. This thesis has therefore investigated the binding characteristics of the human GnRH …
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EFFECT OF CONSTITUTIVELY ACTIVATED LUTEINIZING HORMONE RECEPTOR ON THE MOUSE REPRODUCTIVE SYSTEM
… mutation. Boys with this mutation undergo puberty by 2-4 years, caused by elevated testosterone in the context of prepubertal luteinizing hormone levels and present with Leydig cell hyperplasia. Clinically, these symptoms are associated with familial male-limited precocious puberty (FMPP). …
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The plasma corticosteroids: their determination and normal variations
… life, which can produce syndromes as varied as precocious puberty, virilisation; Addison's disease; Cushing's syndrome, and the newly described hyperaldosteronism syndrome of Conn (1955), a gland which has been implicated in the parthenogenesis of diabetes (Hoet and Lukens, 195; Jackson, 1955), …
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Frankenfoods: Are We Bioengineering Our Children and What Can Curriculum Do?
… are not yet known: however there are links to precocious puberty, cancer, and other illnesses. I inform the public of the importance of understanding the effects of what we are putting into our bodies and the bodies of our children. I posit that we need to educate in a way that enhances our …
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Utilization of early weaning and intrafollicular insemination as methods to improve the reproductive performance of cattle
… cows. Early weaning is a proven way to induce precocious puberty in heifers. Heifers will experience more estrous cycles before breeding, which is associated with increased fertility. In this experiment, heifers were either subjected to early weaning and a high concentrate diet (EW; 106.5±3.4 …
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Safe formulations of polyethylene and polypropylene: Exploring non-estrogenic antioxidants
… problems we face such as cancer, infertility, precocious puberty, and obesity. They have been linked to diabetes, asthma, neurological misdevelopment and increased aggression. The estrogenic components may be residual monomers, small oligomers, plasticizers, antioxidants or other additives. …
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Intrinsic Neuronal Plasticity of Kiss1 Neurons in Mice around Puberty
Puberty is a critical stage in mammalian development, characterized by rapid somatic growth, sexual maturation, and the final maturation of the central nervous system. The timing of puberty is crucial, as initiating it either too early or too late can lead to adverse outcomes. Precocious puberty …
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Risk factors and protective factors for depression in early maturing females
… It was hypothesized that females who reached puberty earlier than their peers as well as females growing up in a one-parent household, with the biological father absent, would experience more depressive symptoms than females who reached puberty later than their peers or were being raised in …
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The transgenerational effects of Di(2-ethylhexyl) phthalate on female reproduction in mice
… that prenatal and ancestral DEHP exposure caused precocious puberty and disrupted normal estrous cyclicity in all three generations of mice. I also observed changes in birth outcomes such as increased litter size in the F2 generation and increased percentage of female pups per litter in the F3 …