Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Prebiotic chemistry"”.
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Carbonyl Catalysis: Hydrolysis of Organophosphorus Compounds and Application in Prebiotic Chemistry
… crucially important in many aspects in organic chemistry. Many approaches were developed for asymmetric organophosphorus compounds. In this work, different types of organophosphorus compounds were used as the substances for aldehyde-catalyzed hydrolysis reactions. The first part of this thesis …
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Late accretion to the early Earth and rocky exoplanets
… long been speculated to provide a key source of prebiotic feedstock molecules, required for the origins of life. Late accretion may therefore have profoundly controlled the emergence of habitable conditions on Earth, and the prebiotic chemistry that led to the emergence of life. Yet, our …
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Layered Double Hydroxides: Morphology, Interlayer Anion, and the Origins of Life
… reaction is an important reaction of classical prebiotic chemistry. This reaction has been shown to give rise to amino acids, purines and pyrimidines. At cyanide concentrations similar to that expected on the early earth, hydrolysis to formamide rather than self-addition occurs. One theory to …
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Phosphorus Pathways In Deep Time
… by combining insights from planetary science, geochemistry, and biology. The element phosphorus (P) is limiting for life in many environments on the modern Earth. Changes in global P availability may have played a large role in shaping biogeochemical evolution. Moreover, the baseline availability …
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Early evolution of environments and metabolism: insights from nitrogen, selenium and sulfur isotopes
… environments and processes were involved in prebiotic chemistry. We conclude that the origin of life can be more plausibly explained if the various building blocks of living cells slowly emerged from global geochemical cycles. In the second part of my thesis (Chapters 2-3), I explore how …
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The evolution and diversity of noncanonical microbial nitrogen metabolisms
… and commercial significance of nitrogen biogeochemistry has prompted substantial study of the modern nitrogen cycle, but much remains unknown about the evolution of nitrogen biochemistry through deep time. This thesis explores the evolution and nature of divergent or noncanonical nitrogen …
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Prebiotic assembly and replication of nucleic acids
… have been attempted under purportedly plausible prebiotic conditions in the laboratory. For example, polymerization of monomer units of RNA directed by base pairing interactions with an RNA template strand has been achieved in the absence of enzymes through a process called template-directed …
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Characterization of a Novel Dynamic Combinatorial Depsipeptide System with Implications for the Origin of Biopolymers
… together are not easily broken in plausibly prebiotic settings, a kinetic limitation that strongly inhibits dynamic sequence space sampling for peptides and proteins even in modern-day laboratory applications. This hardened chemical nature of proteins suggests that although their constituent …
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Potential prebiotic roles of (amino-)acylation in the synthesis and function of RNA
… (acetyl-RNA). It was suggested that RNA emerged prebiotically via acetyl-RNA and also is proposed to have favourable genotypic properties due to greater propensity to form duplex structure. To study the properties of acetyl-RNA, their synthesis by solid-phase chemistry was required and described …
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Emergence, survival, and selection of metal-binding peptides in the prebiotic environment
Metabolism is a subset of chemistry that allows cells to defy thermodynamic equilibrium, a fundamental process that must have been in place from the very beginning of biology. Before evolution produced efficient catalysts in the form of complex protein machinery, short metal binding peptides might …