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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 49 for “"Pre-implantation"”.

  1. Mitochondrial DNA replication in pre-implantation embryonic development

    Spikings, Emma CatherineUniversity of Birmingham2007

    … replication is highly regulated in oocytes, pre-implantation embryos and embryonic stem cells (ESCs) and that this may be disrupted following nuclear transfer (NT). MtDNA copy number decreased between 2-cell and 8-cell staged porcine embryos and increased between the morula and expanded …

    birmingham Repository record

  2. Pre-implantation Abnormalities in the Mouse and Opossum Ovum

    Machlis, Gertrude RaffertyUniversity of Illinois at Urbana-Champaign1947

    uiuc Repository record

  3. A comparison of attitudes towards prenatal diagnosis and pre-implantation genetic diagnosis

    Miller, Chloe LouiseUniversity of Leeds2010

    Technological advances in prenatal screening and diagnosis mean that it is now possible to test for a wide range of congenital conditions (Hewison et al., 2007). Traditionally testing has been carried out during pregnancy (prenatal diagnosis, PND). However, advances in technology have made it …

    whiterose Repository record

  4. Quality assessment in renal transplantation: Methods of optimising pre-implantation biopsy assessment

    Ayorinde, JohnUniversity of Cambridge2022

    [Restricted]

    cambridge Repository record

  5. Investigating the consequences of chromosome abnormalities arising during pre-implantation development of the mouse

    Bolton, Helen LouiseUniversity of Cambridge2014

    The majority of human pre-implantation embryos created through in vitro fertilization (IVF) are mosaic as they are constituted of a mixture of diploid and aneuploid cells. Chromosome abnormalities are widely believed to contribute towards the relatively low success rates of IVF treatment. …

    cambridge Repository record

  6. “It is better to have tried, no matter what” : Psychological perspectives on pre-implantation genetic diagnosis (PGD)

    Järvholm, Stina2017

    … options when they wish to become parents. Pre-implantation genetic diagnosis (PGD) combines in vitro fertilization (IVF) with biopsy of the embryo. With PGD the couple can start a pregnancy knowing that the child will not be affected by the particular disease. PGD is however a difficult way …

    goteborg Repository record

  7. ESTABLISHMENT IN CULTURE OF MOUSE AND HUMAN STEM CELLS WITH EXPANDED FATE POTENTIAL

    Ryan, David JohnUniversity of Cambridge2018

    … a self-renewing state that possessed features of pre-implantation blastomeres. I succeeded in formulating a novel hypothesis driven cell culture medium which allowed the establishment of a stem cell state that possessed expanded differentiation potential to the embryonic and both extra-embryonic …

    cambridge Repository record

  8. Leukemia Inhibitory Factor (LIF): Murine Preimplantation Embryo Development, Implantation Rates, and Skeletal Development

    Mitchell, Michael Hayes2019

    … has been demonstrated that LIF is essential for implantation in mice. Little is known relating to the manner by which LIF effects pre-implantation and post-implantation development. The objectives of this project were to determine the effects LIF on pre-implantation development, to determine the …

    odu Repository record

  9. DNA methylation in early mammalian development

    Chan, Michelle M. (Michelle Mei Wah)Massachusetts Institute of Technology2013

    … genome-scale DNA methylation profiles across pre-implantation development to identify the targets and characterize the dynamics of global demethylation that lead to totipotency and the subsequent changes to embryonic specification. In Chapter 1, I validate and refine the decades old model for …

    mit Repository record

  10. Transnational biopolitics and family-making in secrecy : an ethnography of reproductive travel from Turkey to Northern Cyprus

    Mutlu, Burcu,Ph. D.Massachusetts Institute of Technology.Massachusetts Institute of Technology2019

    … namely, donor gametes and sex selection through pre-implantation genetic diagnosis - that are legally unavailable in Turkey. By combining anthropology of secrecy with feminist studies of assisted reproductive technologies, this dissertation argues that Turkey's ban on gamete donation has helped …

    mit Repository record

  11. Role of Endoplasmic Reticulum Stress in Trophoblast Stem Cell Differentiation

    Capatina, NadejdaUniversity of Cambridge2019

    … (TSCs), placental development, and subsequent pregnancy outcome. To address this question, I first used an in vitro mouse TSC model. Morphological observations suggest that upon ER stress, TSCs lose stemness by differentiating into specialized trophoblast cell subtypes. Second, I used an in …

    cambridge Repository record

  12. The Role of Merlin and Apicobasal Polarity In Endometrial Development and Homeostasis

    Lopez, Erin, <p>0000-0001-9449-2269</p>2019

    … are necessary to secrete nutrients for the pre-implantation embryo. In addition, the endometrial gland is thought to be where endometrial cancer originates. While the endometrium is important for female fertility, relatively little is understood about how glands develop or how endometrial …

    uthsc Repository record

  13. The Experiences of Women Who Live with an Implantable Cardioverter-Defibrillator (lCD)

    Smith, Jenea Mary2009

    … Despite its established health benefits, lCD implantation is accompanied by psychological factors which merit research attention. This study investigated the experiences of women who live an lCD. The homogenous, purposeful sample consisted of 15 women who had an lCD that was implanted within …

    unf Repository record

  14. DNA Methylation Landscape of the Fibrinogen Gene Cluster in the Equine Embryo

    Grant, Danielle MagannGraduate Studies2018

    The initial weeks of equine pregnancy includes the unique phase of embryo mobility from day 9 until fixation on day 15. Fixation of the embryo to the uterine wall occurs before a microvillous attachment at ~day 40. Throughout the mobility period the equine embryo expresses and secretes fibrinogen, …

    calgary Repository record

  15. The physiological significance of insemination in programming pregnancy outcome

    Bromfield, John James2006

    … molecular environment of the uterus during the pre - and peri - implantation period of early pregnancy is critical for implantation success and optimal fetal and placental development. Perturbations to this environment not only have consequences for the success of pregnancy and neonatal health …

    adelaide Repository record

  16. Increasing Professional Interpreter Use To Improve Patient Outcomes On The Inpatient Oncology Unit

    Medina, Kimberly

    … and utilization of professional interpreter services for LEP patients in the in-patient setting. The implementation was 10 weeks on an in-patient oncology unit in a Level one tertiary medical center in the northeastern United States. This included pre-implantation education, data …

    yale Repository record

  17. ANALYZING THE POTENTIAL IMPACT AND ETHICAL QUESTIONS SURROUNDING CRISPR-CAS9 IN EMBRYONIC GENOME EDITING

    Hanamirian, Michael AlbertWake Forest University2018

    … Procedures such as in vitro fertilization and pre-implantation genetic diagnosis can help determine this cost, as these technologies are precursor steps to embryonic genome editing. Next, it covers the many questions and ethical concerns associated with using embryonic genome editing to treat …

    wfu Repository record

  18. Notchless Interacts with Multiple Signaling Pathways during Mouse Peri-Implantation Development

    Lo, Chiao-Ling

    <p>During peri-implantation, the embryo transitions from a suspension environment in the fallopian tubes to an adherent system within the uterus. Successful transition requires maternal and fetal signaling cascades that establish maternal-fetal boundaries. Failure is common, as ~ 25% of all human …

    purdue-thes Repository record

  19. Murine embryonic stem cells and hypoxia : growth kinetics, metabolism, and plating efficiency

    St. Laurent, Daryl, 1979-Massachusetts Institute of Technology2004

    … a hypoxic environment. These cells come from the pre-implantation embryo, whose native environment is the hypoxic mammalian reproductive tract. Growing stem cells in an environment with higher oxygen levels (i.e. the atmospheric oxygen levels that are normally used to cultivate stem cells) could …

    mit Repository record

  20. A study of acetylcholinesterase and cholinesterase in the fetal mouse brain and a study of the effects of three teratogens, vitamin A, cyclophosphamide and sodium valproate on the fetal mouse central nervous system

    Pillans, Peter IanDivision of Clinical Pharmacology1987

    … to examine new markers for the evaluation and prediction of the teratogenic potential of drugs, and (ii) to try and throw more light on pathogenic mechanisms of drug injury with particular reference to the developing fetal central nervous system. Acetylcholinesterase activity in brain …

    cape-town Repository record

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