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Showing 1 to 1 of 1 for “"Pré-stimulation avec des cytokines"”.

  1. Cytokine priming enables triggering of naive auto-reactive CD8[superscript +]T cells by weak agonist ligands of the TCR

    … T cells undergo proliferation without antigenic stimulation through a process referred to as lymphopenia-induced proliferation (LIP). LIP of naive CD8[superscript +] T cells requires IL-7 and a self peptide presented by MHC-I, which implies that TCR signaling is needed for LIP of naive …

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