Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Powder formulation"”.
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Needle-free drug delivery using shock wave techniques
… of devices capable of epidermal delivery of powder medications. These devices use high-pressure compressed gas to accelerate drug particles 2 to 50 gpm in size to velocities of 200 to 1000 m/s. At these speeds the particles have sufficient momentum to penetrate the skin barrier and reach the …
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Influence of plasma proteins on setting characteristics of mineral trioxide aggregate like cement
… of an MTA-like dental cement. The cement powder formulation was mixed with the liquid phase containing normal plasma protein concentrations or quarter, double or quadruple the normal plasma protein concentration as well as a mixture of all three proteins. Compressive strength and relative …
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Computational Modelling and Optimization of Dry Powder Inhalers
Dry powder inhalers (DPIs) are a common therapeutic modality for lung diseases such as asthma, but they are also used to treat systemic diseases such as diabetes. Advantages of DPIs include their portable design and low manufacturing costs. Another advantage of DPIs is their breath activation, …
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Formulation development of a novel antivirulence compound for enhanced pharmacokinetic properties
… However, its clinical use is restricted by formulation challenges arising from its poor aqueous solubility. In this dissertation, plate-like or tube-like C790 nanoparticles with thickness down to one hundred nanometers have been successfully produced using antisolvent precipitation- …
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Nasal delivery of peptides using powder carriers based on starch/poly(acrylic acid)
… also mentioned. This research project focused on powder formulations as carriers for the nasal delivery of peptides, aiming to improve the nasal bioavailability by enhancing the residence time of the drug in the nasal cavity by incorporating viscosity-enhancing excipients in the formulation. As …
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Pharmaceutical analysis and in-vitro aerodynamic characterisation of inhaled theophylline formulations containing drug particles prepared by supercritical fluid processing. Chromatographic, spectroscopic, and thermal analysis of micron-sized theophylline particles prepared by supercritical fluid technology and in-vitro evaluation of their performance as inhaled dry powder formulations.
… performance of a new inhaled theophylline formulation prepared by supercritical fluids technique. For the analysis of the output from the in-vitro tests (and further in-vivo tests) a new, fast, sensitive high performance liquid chromatographic (HPLC) method was developed and validated for …
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Development of a platform for nasal delivery of peptides and vaccines using powder carriers based on starch/poly(acrylic) acid
… acid-based polymer (Carbopol® 974P) was used as powder carrier to amplify the mucoadhesive capacity of the formulation. In a first part of the study, the Amioca®/Carbopol® powder formulation was subjected to a heat treatment procedure. After heat treatment the water-absorbing capacity, viscosity …