Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Postnatal exposure"”.
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Changes in Hippocampal Plasticity and HPA Axis Function Following Postnatal Exposure to Di(2-Ethylhexyl) Phthalate in Rats
Phthalates are known to affect the development of regions within the hippocampus, however the mechanisms of these toxic effects are not well known. Stress is also known to have detrimental effects on the hippocampus. This study aimed to determine whether phthalates affect hippocampal development, …
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THE INTERPLAY BETWEEN ENDOCRINE DISRUPTION AND GENETICS IN THE PHYSIOPATHOLOGY OF HUMAN NEURODEVELOPMENT: BRIDGING EPIDEMIOLOGY TO MOLECULAR INSIGHTS THROUGH BRAIN ORGANOIDS AND HIGH RESOLUTION OMIC MODELLING
… studies uncovered a strong link between pre- and postnatal exposure to EDCs and impaired development of cognitive functions, attention and social behaviors in children. Nonetheless, the molecular mechanisms underlying such outcomes are yet to be detailed and EDC-induced DNT (developmental …
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Nutritional and Health Consequences of Feeding Diets of Varied Macronutrient Composition and Subjected to Select Processing Conditions in Domestic and Wild Felids
… Study 4 determined the effects of in utero and postnatal exposure to high-protein or high-carbohydrate diets on adipose tissue gene expression, blood metabolites, and physical activity levels in domestic kittens. Study 5 determined the effects of ovariohysterectomy on body composition, adipose …
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Microglial dysfunction as an early susceptibility to Alzheimer's disease: the exacerbating role of developmental toxicity
… within the context of AD. We hypothesized that postnatal toxicant exposure in a mouse model of AD (Tg) would disrupt neuroimmune development preferentially in females, in parallel with human AD sex bias, incurring altered regulation of microglial response phenotypes early in life that then …
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Auditory-Visual System Interactions: Perinatal Visual Experience Affects Auditory Learning and Memory in Bobwhite Quail Chicks (Colinus virginianus)
… emergent sensory systems throughout prenatal and postnatal development. It has also been shown that young infants can learn perceptual information during perinatal development. However, the exact nature of the relationship between prenatal and postnatal perceptual development and the role of early …
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The gut-brain axis in seizure susceptibility: A role for microbial metabolite S-equol
… in neuronal excitation following S-equol exposure. We additionally characterize entorhinal cortex (ECTX) pyramidal neuronal hyperexcitability, and demonstrate the ability of exogenous S-equol to ameliorate CNS-infection-induced ECTX neuronal hyperexcitability ex vivo. Finally, we …
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Essays on early childhood development and family economics
… how policies can compensate for both pre- and postnatal exposure to maternal substance use in children under twelve years old.
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Indoor air pollution and environmental tobacco smoke exposure in a South African birth cohort study
… care visits and hospitalisation. Environmental exposures to indoor air pollution (IAP) or tobacco smoke are important risk factors for childhood respiratory disease. Despite increased electrification, many communities in LMIC rely on alternate fuel sources for household cooking or heating. The …
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The Effects of Early Postnatal PCP Administration on Performance in Locomotor Activity, Reference Memory, and Working Memory Tasks in C57BL/6 Mice
… Thus, several labs have attempted to use early postnatal PCP administration in rodents as a drug model of schizophrenia. The current study investigated the cognitive effects of early postnatal PCP administration in C57BL/6 mice. Mouse pups received daily administrations of either 10.0 mg/kg PCP …