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Showing 1 to 3 of 3 for “"Postmortem Brain Tissue"”.

  1. Generating Predictive Gene Expression Signatures for Alzheimer's Disease Using Postmortem Brain Tissue

    … These pathological features develop in specific brain regions, but why some areas are more vulnerable to early AD-related changes remains unclear. To address this, predictive gene expression signatures were developed to explore the molecular mechanisms underlying regional susceptibility to AD …

    chapman Repository record for Generating Predictive Gene Expression Signatures for Alzheimer's Disease Using Postmortem Brain Tissue (opens in a new tab)

  2. Astrocytic Contribution to the Glutamatergic Transmission in Schizophrenia

    … systems and various cortical and subcortical brain structures, albeit with no unifying/overarching hypothesis connecting the existent knowledge. Moreover, no current animal model or biological construct reproduces the complexity of the disease with acceptable validity. In my work I have taken …

    utswmed Repository record for Astrocytic Contribution to the Glutamatergic Transmission in Schizophrenia (opens in a new tab)

  3. Preparation, characterisation and transcriptome analysis of RNA frm human vCJD brains.

    … Creutzfeldt-Jakob disease (vCJD) in the human brain remain poorly understood. Gene expression data may provide insight into the molecular mechanisms involved. This requires analysis of human postmortem brain tissue however; the variability in RNA preparations from human brain material is a …

    edinburgh Repository record for Preparation, characterisation and transcriptome analysis of RNA frm human vCJD brains. (opens in a new tab)