Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 232 for “"Positron emission tomography"”.
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Compressive Sensing in Positron Emission Tomography (PET) Imaging
Positron emission tomography (PET) is a nuclear medicine functional imaging modality, applicable to several clinical problems, but especially in detecting the metabolic activity (as in cancer). PET scanners use multiple rings of gamma ray detectors that surround the patient. These scanners are …
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Evaluation of yttrium-90 positron emission tomography dosimetry
… of <sup>90</sup>Y has been shown to allow for positron emission tomography (PET) imaging following radioembolization. This work explores the accuracy and limitation of <sup>90</sup>Y PET imaging due to the extremely low signal to noise (SNR) ratio associated with <sup>90</sup>Y and verifies the …
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Positron Emission Tomography in Oncology and Environmental Science
… nature of a biological environment is the use of positron emission tomography (PET). Excitingly, the efforts of the nuclear medicine community over the past two decades have resulted in a remarkable surge in the use of PET, establishing it as a standard practice and part of routine care in …
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Motion Detection in Dynamic Cardiac Positron Emission Tomography Images
… cardiac 82Rb PET images.First, we determined if positron-emitting fiducial markers can be used as surrogate markers for heart motion in dynamic PET images. Second, algorithms were developed to track fiducial marker motion. Lastly, we tested the idea that principle component analysis may be able …
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Functional lung imaging in humans using Positron Emission Tomography
… with a method of functional lung imaging using Positron Emission Tomography (PET). In this technique, a radioactive tracer, nitrogen-13, is dissolved in saline solution, and injected into a peripheral vein. By analysis of the tracer kinetics through the lung, measured using PET, a …
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Positron Emission Tomography Phantom Studies for Radiation Therapy Target Delineation
… prevalent in radiation treatment planning (RTP). Positron Emission Tomography (PET) is one form of bioanatomic imaging that is readily used for RTP of non-small-cell lung cancer (NSCLC) and head and neck cancer (H&N). PET utilizes a radiotracer, such as fluro-deoxy glucose (FDG), to detect tumors. …
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Design, Synthesis, and Evaluation of Novel Positron Emission Tomography Radiotracers
… patient outcomes through the development of positron emission tomography (PET) radiotracers that could be used for therapy planning. The goal of the first project was to design, synthesize, and evaluate PET radiotracers that could measure the enzymatic activation of Irinotecan (CPT-11), a …
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Approaches for respiratory motion compensation in positron emission tomography imaging
… blur and inaccurate quantitation results in positron emission tomography (PET) imaging. Traditional gated acquisition approach corrects motion artifacts by generating a snapshot sequence. Each snapshot, however, is of poor image quality due to insufficient photon counts. This dissertation …
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Novel positron emission tomography applications for imaging cardiovascular disease activity
… can now be imaged using 18F-sodium-fluoride positron emission tomography and computed tomography which targets microcalcification (diameter <50 μm), providing different information to established macroscopic calcification (minimum diameter 200 to 500 μm) imaged with computed tomography. …
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Design study of an organ-dedicated positron emission tomography system
Whole-body positron emission tomography (PET) has been widely used for cancer diagnosis and treatment, but its low spatial resolution limits the management of cancers in specific organs or regions. To promote the pre-clinical and clinical research and improve the diagnosis accuracy and treatment …
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Imaging atherosclerotic plaque inflammation with [18F]- fluorodeoxyglucose positron emission tomography
Inflammation is important in both the pathogenesis and outcome of atherosclerosis. Plaques containing numerous inflammatory cells, particularly macrophages, have a high risk of rupture, whereas those with fewer inflammatory cells are at lower risk. The current ‘gold standard’ technique for imaging …
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Atherosclerotic inflammation imaging using somatostatin receptor-2 positron emission tomography
… by 18F-fluorodeoxyglucose (FDG) PET-computed tomography (CT), as a glucose analog, high 18F-FDG signal spillover owing to physiological myocardial muscle metabolism prevents reliable coronary interpretation. Lack of cell specificity, and the influence of hypoxia on 18F-FDG uptake within …
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Towards Robust Radiomic Markers from Positron Emission Tomography in Cancer
[18F]-fluorodeoxyglucose positron emission tomography ([18F]-FDG PET) images contain both rich and untapped information regarding diseases such as cancer. The latter can be accessed computationally using radiomics, from which we can build new markers of disease to improve the clinical management of …
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Quantitative Positron Emission Tomography for Estimation of Absolute Myocardial Blood Flow
<p>Myocardial perfusion imaging (MPI) with positron emission tomography (PET) is an emerging clinical tool for diagnosis and characterization of ischemic heart disease. The increasing use of PET introduces an opportunity, as it is capable of providing quantitative images that can be analyzed with …
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Quantitative functional brain imaging with Positron Emission Tomography and irreversible tracers
This thesis presents SAIF, (Spectral Analysis with Iterative Filter),<br/>a SA-based method for the quantification of PET data investigated with<br/>irreversible-uptake tracers. SAIF has been designed in order to maintain<br/>the main advantages of SA but providing a superior robustness to …
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Quantification of pulmonary physiological parameters for use with positron emission tomography
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2002.
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Monte-Carlo simulations of positron emission tomography based on liquid xenon detectors
The prospects for enhanced Positron Emission Tomography imaging using liquid xenon (LXe) gamma ray detectors had been examined. Monte-Carlo simulations using GEANT4 were performed and the results were used to study the expected performance of a small animal PET scanner in comparison with a …
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System Solution for In-Beam Positron Emission Tomography Monitoring of Radiation Therapy
In-beam Positron Emission Tomography (PET) is a system for monitoring high precision radiation therapy which is in the most cases applied to the tumors near organs at risk. High quality and fast availability of in-beam PET images are, therefore, extremely important for successful verification of …
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Positron emission tomography in vivo characterisation of the pathology of frontotemporal dementia
… and group analysis of FTD syndromes, using positron emission tomography (PET) radioligands to visualise and quantify different aspects of pathophysiology in vivo. [18F]AV-1451tau was introduced primarily to study tau pathology in Alzheimer’s disease using, which differs from FTD tauopathy in …
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