Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Portal of entry"”.
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Comparison of Potential Salmonella Portals of Entry and Tissue Distribution Following Challenge of Poultry
… by the fecal-respiratory route may be a viable portal of entry for Salmonella and could explain some clinical impressions of relatively low-dose infectivity under field conditions in relation to the requisite high oral challenge dose that is typically required for infection of poultry through …
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HIV pathogenesis in the female genital tract during chronic HIV infection : the impact of inflammation, T cell memory differentiation status and homeostatic cytokines on mucosal T cell immunity
The female genital tract serves as the major portal of entry for human immunodeficiency virus (HIV). Local immune factors unique to the mucosal micro-environment such as the genital tract cytokine milieu or the activation/differentiation status of T cells may play a significant role in heterosexual …
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The streptococcal collagen-like protein-1 (Scl1) is a multifunctional adhesin in extracellular matrix interactions, biofilm formation, and host colonization by group A Streptococcus
… are susceptible to the introduction of GAS and serve as a portal of entry. The nutritional nature of a wound and the accessibility to exposed host cell surfaces and extracellular matrix components create a model milieu for successful host colonization and potential biofilm formation. …
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An Investigation into the Use of a Plant-Expressed Virus-Like Particle as an Oral Vaccine Candidate
… virus-like particles (VLPs) could offer an alternative method for the oral delivery of vaccines. VLPs' robustness, combined with their compartmentalisation within the plant cells, should favour their stability in the harsh gastro-intestinal (GI) environment. In the small intestine, …
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Early pathogenesis of Yersinia ruckeri infections in rainbow trout (Oncorhynchus mykiss, Walbaum)
Yersinia ruckeri is the causative agent of yersiniosis or enteric redmouth disease (ERM) and causes significant losses in salmonid aquaculture worldwide. Although infection with this agent has been reported in other fish species, salmonids and especially rainbow trout are most susceptible to ERM. …
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Characterization of the MexT Regulator of the mexEF-oprN Multidrug Efflux Operon of Pseudomonas aeruginosa
… multidrug efflux systems in this organism. One of these, MexEF-OprN, exports chloramphenicol, fluoroquinolones and trimethoprim and is positively regulated by MexT, encoded by the mexT gene that is located upstream of the efflux genes. MexT also positively regulates the mexS gene that encodes an …
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Human enteroids as a model for infectious disease
… gastrointestinal (GI) tract is a major site of host-pathogen interactions. As such, many human pathogens have evolved to either use the GI tract as a portal of entry to gain access to distal sites in the body or cause acute disease within the GI tract. For many years we lacked a suitable cell …
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The source, cost and prevention of central venous catheter-related infection
… venous catheters have become an integral part of patient management however they are associated with many complications including infection. Despite efforts being made to reduce the incidence of such infect ions the problem continues to increase and has resource implications for the Health …
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Effects of Chronic High Sucrose With Dietary or Drinking Inclusion on the Electrogenic Glucose Absorption in the Intestinal Tract of Mice (Mus musculus)
The long-term impact of high sugar diets, a factor in the development of obesity and type-2 diabetes, on the intestinal electrogenic sodium dependent glucose transport, the first portal of entry for glucose, is unknown. Here female C57bl/6 mice fed a normal standard chow diet, and 20% sucrose in …
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Effect of Advanced Age on the Innate Immune Response to Cutaneous Wound Infection
… in US health care expenditure is spent on care of chronic, non-healing wounds. The failure to effectively heal wounds is often compounded by co-morbidities, such as diabetes or obesity. Another major patient population afflicted with chronic wounds are the elderly. Advanced age is associated …