Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 42 for “"Porphyromonas gingivalis"”.
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Stress response of porphyromonas gingivalis
The heat shock response of Porphyromonas gingivalis was examined by one-and two-dimensional polyacrylamide gel electrophoresis after metabolic labeling with (14C)-amino acids. When P. gingivalis cells were shifted from 37°C to 42°C, elevated synthesis of four proteins with the apparent molecular …
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The Characterization of PG0228 in Porphyromonas gingivalis W83
… can contribute to numerous systemic diseases. Porphyromonas gingivalis, a gram-negative anaerobic bacterium, is a recognized prime causative agent in periodontitis. Studies have shown a number of small non-coding RNAs (sRNAs) have been related to bacterial virulence. Many of these sRNAs require …
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Mechanisms of Virulence Regulation in Porphyromonas gingivalis W83
… that expression is tightly controlled. <em>Porphyromonas gingivalis</em> has been associated with adult periodontitis and in the development of many systematic diseases. The major virulence factors of <em>P. gingivalis</em>, the gingipains, are responsible for pathogenesis including …
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HcpR of Porphyromonas gingivalis utilizes heme to bind NO
The obligate anaerobe Porphyromonas gingivalis is the etiological agent responsible for periodontal disease. It must withstand high levels of reactive nitrogen species in the oral cavity generated by the host and other oral flora. The mechanisms allowing for protection against such stress remain …
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Role of Extracytoplasmic Function Sigma Factors in Porphyromonas gingivalis
<p>Porphyromonas gingivalis is a major etiological agent that is responsible for the cause and progression of periodontal diseases. The bacterium is exposed to various environmental conditions and oxidative stress conditions while it is in the oral cavity. So, P. gingivalis should have an efficient …
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Investigating the transcriptional regulation by OxyR in Porphyromonas gingivalis.
… associated with these diseases. One of them is Porphyromonas gingivalis belonging to the phylum Bacteroidetes. Infection by P. gingivalis is recurrent after physical removal of the bacteria from the oral cavity and even after antibiotic treatment as development of resistance is not rare. Hence …
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The study of cell surface components on Porphyromonas gingivalis
Porphyromonas gingivalis plays a major role in mixed bacterial infections of the periodontium. The objective of the study was to clone genes encoding, and characterize cell surface components of P. gingivalis as potential virulence factors of this organism. AP. gingivalis ATCC 33277 genomic library …
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Mechanisms of Oxidative Stress Resistance in Porphyromonas gingivalis W83
<p><em>Porphyromonas gingivalis</em>is one of the most important bacterial etiological agents involved in adult periodontitis. It possesses several virulence factors which aid in its persistence in the periodontal pocket leading to the development of some systemic illnesses. As an anaerobe, <em>P. …
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Role of VimF in Gingipain Maturation in Porphyromonas gingivalis
Gingipain activity in Porphyromonas gingivalis, the major etiological agent in adult periodontitis, is post-translationally regulated by unique Vim proteins including VimF, a putative glycosyltransferase. To ascertain the VimF mediated phenotype we first inactivated the vimF gene in P. gingivalis …
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Role of VimA in Cell Surface Biogenesis in Porphyromonas gingivalis
<p><em>Porphyromonas gingivalis </em>is an important etiological agent of periodontal disease - a disease that affects an estimated 49,000,000 people in the United States of America. Periodontal disease includes gingivitis – inflammation of the gums, and periodontitis – destruction of the teeth and …
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Study on porphyromonas gingivalis- and porphyromonas endodontalis- mediated signaling pathway
It is known that anaerobic microbes like Porphyromonas gingivalis (P. gingivalis) are involved in the progression and initiation of multiple forms of periodontal disease such as chronic periodontitis. However, in order to culture this gram-negative anaerobic microbes in the laboratory we need a …
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ROLE OF CAPSULE IN THE INTERACTION OF PORPHYROMONAS GINGIVALIS WITH HOST
… triggered by bacteria. One of these bacteria is Porphyromonas gingivalis. Some strains of P. gingivalis produce capsule, however, so far the role of capsule in the interactions with host cells in P. gingivalis is not well understood. Here, we investigated the contribution of capsule to triggering …
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DNA Repair of 8-oxo-7,8-Dihydroguanine Lesions in Porphyromonas gingivalis
The persistence of Porphyromonas gingivalis in the inflammatory environment of the periodontal pocket requires an ability to overcome oxidative stress. DNA damage is a major consequence of oxidative stress. Unlike other organisms, a non-base excision repair mechanism for the removal of …
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Porphyromonas gingivalis: A Methodology for Culturing, Extracting, and Identifying Fimbriated Strains
Background/purpose – Fimbriated Porphyromonas gingivalis has been shown to contribute to periodontitis, atherosclerosis, and arthritis. While many studies have been done on the bacterium itself, there is little information on selectively culturing and identifying P. gingivalis from a sulcal swab. …
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An investigation of Porphyromonas gingivalis peptidylarginine deiminase: a putative virulence factor in an animal model of inflammation.
Porphyromonas gingivalis, an oral periodontopathogen linked to chronic periodontitis expresses peptidylarginine deiminase (PAD), an enzyme that converts peptide-bound arginine to citrulline. A relationship between human PADs and chronic inflammatory diseases has been proposed. Citrullinated …
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PART I CRYSTAL STRUCTURE OF A DIMERIZATION DOMAIN OF DROSOPHILA CAPRIN. PART II CHARACTERIZATION OF TWO CAS13B CRISPR-CAS SYSTEMS FROM PORPHYROMONAS GINGIVALIS
PART I: CRYSTAL STRUCTURE OF A DIMERIZATIO DOMAIN OF DROSOPHILA CAPRIN Drosophila Melanogaster Caprin (dCaprin) shares conversed HR1 domain with Caprin protein family members, which are RNA binding proteins that play critical roles in many important biological processes, such as synaptic …
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LPS from subgingival plaque and the periodontal pathogen Porphyromonas gingivalis, its effect on M1 and M2 macrophage responses and potential as a biomarker
… bacteria, including keystone periopathogen Porphyromonas gingivalis (PG) is able to modify the bio-reactive lipid-A portion of LPS which in turn modifies immune response. The aims of this study were to characterise lipid-A profiles from subgingival plaque and PG LPS and determine their …
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Microbiology of periodontal disease in Singapore and the discovery of a bacterial intron in Actinobacillus actinomycetemcomitans
… Actinobacillus actinomycetemcomitans cdt; Porphyromonas gingivalis prtC and Tannerella forsythensis (Bacteroides forsythus) prtH genotypes correlated well with the periodontal status of the local population. A. actinomycetemcomitans possesses the cytolethal-distending toxin (CDT). The 2.1 …
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Relationship of Periodontal Status and Periodontal Infection with Coronary Artery Disease // Връзка на пародонталния статус и пародонталната инфекция с коронарната болест
… Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Treponema denticola, on periodontal and cardiac clinical indicators was also investigated. We found that the severity of periodontitis is associated with a more frequent presence of coronary artery atherosclerosis, and …
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Risk factors for preperiodontitis in adolescents
… (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannerella forsythia, Prevotella intermedia, Prevotella nigrescens and Treponema denticola) ja syljen parodontiittibiomerkkiaineet (MMP-8, PMN elastaasi, proteiini, albumiini, IgA, IgG, and IgM). Tulosten analysoinnissa …
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