Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Porcine epidemic diarrhea virus"”.
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Immune response to and pathogenesis of porcine epidemic diarrhea virus
<p>Porcine epidemic diarrhea (PED) virus causes effusive diarrhea in pigs of all ages and high mortality among pre-weaning pigs. The PED virus (PEDV) is one of several important swine pathogens, which causes significant economic losses to the swine industry. The first outbreak of PED in the United …
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Innate immune evasion and interferon antagonism by porcine epidemic diarrhea virus
Porcine epidemic diarrhea (PED) is a highly contagious and acute enteric disease of swine featured by vomiting, watery diarrhea, and severe dehydration causing high mortality in piglets. In the U.S., PED emerged for the first time in 2013 and severely affected most pig-producing states. The …
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Vaccine Development Against Porcine Epidemic Diarrhea Virus Utilizing the Hepatitis B Virus Core Antigen Protein
Porcine epidemic diarrhea Virus (PEDV) is a virus effecting swine. It is the cause of disease that manifests with symptoms ranging from depression, to severe dehydration and death. Young piglets are particularly susceptible to the virus, which can reach mortality rates of 100%. Presence of the …
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Expression and Purification of the C-Terminal Domain of Porcine Epidemic Diarrhea Virus (PEDV) S1 Protein
Porcine Epidemic Diarrhea Virus (PEDV) was first detected in Europe in the 1970s, but did not emerge in the United States until 2013. When it arrived, it ran rampant due to the lack of previous exposure, causing the death of 7-8 million neonatal piglets and $900 million to $1.8 billion in losses to …
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Characterization of virus strain- and pig age-dependence of porcine epidemic diarrhea virus: Implications for vaccine development
Porcine epidemic diarrhea virus (PEDV) is the causative agent of porcine epidemic diarrhea, an enteric disease affecting pigs of all ages that impacts the global swine industry. Although PEDV was first identified in Europe in 1970s and spread to some Asian countries thereafter, PEDV did not emerge …
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Development and Characterization of A Recombinant Orf Virus Vector Expressing the Spike Protein of Porcine Epidemic Diarrhea Virus
<p>Orf virus (ORFV), the type member of the genus <em>Parapoxvirus</em> of the family <em>Poxviridae</em>, causes orf or cutaneous pustular dermatitis in sheep and goats. ORFV is a ubiquitous virus capable of re-infecting its hosts multiple times over time. ORFV causes a non-systemic, self-limiting …
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Development of Virus-like particles (VLPs) Based Vaccines Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV)
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine epidemic diarrhea virus (PEDV) are two of the most prevalent swine pathogens that have impacted the global swine industry for decades. Both are RNA viruses with increasing heterogeneity over the years, making a vaccine solution …
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Understanding the determinants for substrate recognition, regulation of enzymatic activity and the development of broad-spectrum inhibitors of coronavirus 3-chymotrypsin-like proteases
Coronaviruses include lethal human pathogens like severe acute respiratory syndrome coronavirus (SARS-CoV) and the recently emerged Middle-east respiratory coronavirus (MERS-CoV). Coronavirus also impact global economy by infecting farm animals like pigs (porcine epidemic diarrhea virus, PEDV), …
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Surveillance of Emerging Livestock Viruses
… control strategies. Recent, severe outbreaks of porcine epidemic diarrhea virus (PEDV) in Asia and North America highlighted the need for well-validated diagnostic tests for identification of PEDV infected animals and evaluation of their immune status. PEDV was first detected in the U.S. in May …
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In vitro inhibition of coronavirus replications
"In Vitro Inhibition of Coronavirus Replications A search for new anti-coronaviral drugs to treat coronaviral infections was motivated by an outbreak of severe acute respiratory syndrome (SARS). In order to find drugs that treat coronavirus infections, including SARS, we screened traditional …
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Impact of feed additives in swine diets and the effect of corn particle size on metabolizable energy in gestating sows
… 1) non-treated, individually inoculated virus controls (positive control), 2) 0.33% commercial formaldehyde-based product (Sal Curb; Kemin Industries, Inc.; Des Moines, IA), 3) 0.50% MCFA blend (1:1:1 ratio of C6:0, C8:0, and C10:0, Sigma Aldrich, St. Louis, MO), 4) 0.25%, 5) 0.50%, or 6) …