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Showing 1 to 3 of 3 for “"Porcine aortic valve leaflets"”.
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Effects of Mechanical Forces on the Biological Properties of Porcine Aortic Valve Leaflets
Cardiac valves are dynamic, sophisticated structures which interact closely with the surrounding hemodynamic environment. Altered mechanical stresses, including pressure, shear and bending stresses, are believed to cause changes in valve biology, but the cellular and molecular events involved in …
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Non-linear finite element analyses of the aortic heart valve
Finite element models of the aortic heart valve have been successfully used in the past to gain insight into the mechanics of the valve and to aid in understanding of valve failure. Moreover such models are indispensable tools for further developments in heart valve prosthetic design. In previous …
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The Influence of Normal Physiological Forces on Porcine Aortic Heart Valves in a Sterile Ex Vivo Pulsatile Organ Culture System
The aortic valve functions in a complex mechanical environment which leads to force dependent cellular and tissue responses. Characterization of these responses provides a fundamental understanding of valve pathogenesis. The aim of this work was to develop an ex vivo organ culture system capable of …