Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"Porcine Reproductive And Respiratory Syndrome Virus"”.
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Antigenic profiling of the porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure in sows and boars, and is involved in the porcine respiratory disease complex, causing huge economical losses to the swine industry. Despite the development and broad implementation of vaccines, the virus could …
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Development of subunit vaccines against porcine reproductive and respiratory syndrome virus (PRRSV)
Since emerging in Europe and the US, PRRS has spread globally and become the most significant infectious disease currently devastating the swine industry. In the US alone, the economic losses caused by this disease amount to more than 560 million US dollars every year. Modified-live PRRSV vaccines …
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Evaluation of potential risk factors of porcine reproductive and respiratory syndrome virus transmission.
Abstract summary not available
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Molecular basis of porcine reproductive and respiratory syndrome virus-mediated innate immune suppression
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2017-05-01
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Innate immune modulation and pathogenic basis for porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus causes PRRS which is one of the most economically significant diseases in the swine industry worldwide. PRRSV has the ability to suppress the type I interferon induction to facilitate its survival during infection, and the nsp1 protein of PRRSV …
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Virus-like particles as a vaccine against porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome (PRRS) is the most significant infectious disease currently affecting the swine industry worldwide. Several inactivated and modified live vaccines (MLV) have been developed to curb PRRSV infections. The unsatisfactory efficacy and safety of these …
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Reverse Genetics-based Approaches to Attenuate Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)
Porcine reproductive and respiratory syndrome virus (PRRSV) is arguably the most economically-important swine pathogen. As the emergences of novel virulent strains of PRRSV continue to occur worldwide, rapid vaccine development is the key for effective control of ongoing PRRSV outbreaks. With the …
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Effects of Heat Stress and Porcine Reproductive and Respiratory Syndrome Virus on Metabolism
Heat stress and immune challenge are costly issues to the swine industry causing significant loss in production and health including reduced efficiency in muscle accretion and energy utilization. Alterations to metabolism and immune response may participate in these shortcomings. The study …
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Molecular Mechanisms of Host Responses to Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Infection
Porcine reproductive and respiratory syndrome virus (PRRSV) is arguably the most economically devastating pathogen affecting the global swine industry. Since the emergence of the virus in the late 1980s, vaccination strategies aimed to control the virus have not been very effective. Current …
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Surveillance in contemporary swine herds - the case of porcine reproductive and respiratory syndrome virus (PRRSV)
… means to generate information on the presence and/or distribution of pathogens in animal populations. Fulfillment of this function is ultimately dependent on the program's ability to collect, test, aggregate, and analyze data from individual samples. The problem addressed in this dissertation …
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Interaction of the porcine reproductive and respiratory syndrome virus with the macrophage-specific lectin sialoadhesin
The porcine reproductive and respiratory syndrome virus (PRRSV) causes the economically most important viral disease in swine industry today. The virus is a major threat to swine health worldwide, since it is both associated with the porcine respiratory disease complex and the cause of severe …
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Immune Response of Swine to Porcine Reproductive and Respiratory Syndrome Virus: Laboratory and Field Studies
Porcine reproductive and respiratory syndrome virus (PRRSv) is an arterivirus that has had a significant economic impact on the pork industry in the past few decades. Our studies have focused on three major issues that concern alleviation of this problem. These include utilizing contact exposure to …
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Studies on the Interaction between Porcine Plasmacytoid Dendritic Cells and Porcine Reproductive and Respiratory Syndrome Virus
For over 20 years, porcine reproductive and respiratory syndrome (PRRS) has been the most troubling disease afflicting the pork industry. The main reason for this dissertation is that the pathogen responsible for this disease, PRRS virus (PRRSV), has developed the ability to subvert the immune …
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Studies on the interaction between porcine reproductive and respiratory syndrome virus and its natural host cell
Porcine reproductive and respiratory syndrome virus (PRRSV), an arterivirus, causes a costly global disease of swine. PRRSV infects their alveolar macrophages (AMΦ) resulting in an interstitial pneumonia. The ability of PRRSV to modulate the production of interferon (IFN)a and tumor necrosis factor …
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Ribosome profiling of porcine reproductive and respiratory syndrome virus reveals novel features of viral gene expression
Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus which causes significant economic losses to the swine industry worldwide. Here, the viral translatome was characterised using ribosome profiling (RiboSeq), a high-throughput sequencing-based technique that allows the …
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Mixed Strain Identification of Porcine Reproductive and Respiratory Syndrome Virus in Multiplexed Samples using Nanopore Sequencing
For over thirty years, Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) has been a major contributor to morbidity and mortality in the commercial swine industry across the globe. This highly mutagenic RNA virus causes significant economic losses wherever it is prevalent, leading to $664 …
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Novel approaches to enhance the protective immune responses of vaccines against Porcine Reproductive and Respiratory Syndrome Virus
Since late 1980s, porcine reproductive and respiratory syndrome virus (PRRSV) has emerged as the most economically important swine pathogen affecting pig industries worldwide. Vaccination is the principal means that have been used for prevention of PRRSV infection. However, the currently available …
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Novel approaches towards vaccine developments against porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus
Porcine circovirus type 2 (PCV2) is the causative agent of porcine circovirus-associated disease (PCVAD). Porcine reproductive and respiratory syndrome (PRRS) is caused by PRRS virus (PRRSV). Both PCV2 and PRRSV have caused devastating diseases in the swine industry worldwide, resulting in immense …
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Elucidating the Role of Antigen-presenting Cells in the Immunopathogenesis of the Porcine Reproductive and Respiratory Syndrome Virus
The porcine reproductive and respiratory syndrome virus (PRRSV) is a positive sense single-stranded RNA virus of the arteriviridae family and is one of the most economically devastating pathogens in the swine industry today. The PRRSV was discovered in the early 1990s in Europe and the United …
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Suppression of NK cell-mediated cytotoxicity and immunoenhancement of CD40 ligand against porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most economically important pathogenics affecting swine industry worldwide. PRRSV is a single-stranded and positive sense RNA virus that belongs to the family of the Arteriviridae (genus Arterivirus). PRRSV has a restricted …
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