Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 592 for “"Porcine"”.
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Porcine model of xenobiotic metabolism
… to those in humans. The characterization of porcine drug metabolism genes and the genes involved in regulating drug metabolism can provide insights into human drug metabolic diseases and individual variability of responses toward a drug. The tissue- and stage-specific expression of the …
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Antigenic Relationship of Different Porcine Rotavirus Isolates and the Identification of a New Porcine Strain
The problem. Currently, only one strain of porcine rotavlrus has been reported. This strain, designated OSU, has been attenuated and is currently available as a federally licensed, live oral vaccine for pigs. This study is concerned with the antigenic relationship of the OSU vaccine strain to four …
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Studies on the Interaction between Porcine Plasmacytoid Dendritic Cells and Porcine Reproductive and Respiratory Syndrome Virus
For over 20 years, porcine reproductive and respiratory syndrome (PRRS) has been the most troubling disease afflicting the pork industry. The main reason for this dissertation is that the pathogen responsible for this disease, PRRS virus (PRRSV), has developed the ability to subvert the immune …
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Experimental porcine models of retinal ischemia
… angiography and conventional angiography. The porcine model of pressure-induced retinal ischaemia resulted in multifocal ERG changes typical of retinal ischaemia although there may be a confounding problem of pressure-induced damage. Multifocal ERG may be a useful tool to evaluate retinal …
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Postmortem metabolism in porcine skeletal muscle
Once an animal is harvested for meat, skeletal muscle attempts to maintain ATP at or near antemortem levels. To maintain ATP levels postmortem, stored glycogen is catabolized to produce ATP through glycolysis and possibly oxidative metabolism. Hydrolysis of the produced ATP acidifies muscle until …
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Novel approaches towards vaccine developments against porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus
Porcine circovirus type 2 (PCV2) is the causative agent of porcine circovirus-associated disease (PCVAD). Porcine reproductive and respiratory syndrome (PRRS) is caused by PRRS virus (PRRSV). Both PCV2 and PRRSV have caused devastating diseases in the swine industry worldwide, resulting in immense …
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The effects of acidified pepsin on porcine vocal fold tissue: Developing a porcine model of laryngopharyngeal reflux disease
… hypotheses relating to laryngeal disease because porcine vocal folds are most similar to human vocal folds from a structural, biochemical, neuromuscular, and cellular perspective. By utilizing the pig as a model of laryngeal disease, research involving basic, translational, and clinical questions …
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Hypoxia-induced responses of porcine pulmonary veins.
… project was to investigate hypoxic responses of porcine PVs including the impact of maintenance in culture. Maintenance of PVs in culture conditions for 24 hours increased contraction to hypoxia and inhibited hypoxic relaxation post-contraction. These changes to PV hypoxic responses were thought …
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DNA methylation in the early porcine embryo
… is to study the dynamics of DNA methylation in porcine gametes, clonal cell lines, adult somatic cells, and early embryos produced by using in vivo, in vitro, parthenogenetic, and somatic cell nuclear transfer procedures. Differential Methylation Hybridization microarrays were used to study DNA …
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Analysis of Porcine Immunity in PRRS Virus
… economically and scientifically challenged by porcine reproductive and respiratory syndrome (PRRS). This disease is caused by a recently emerged virus of swine (PRRSV) that has been classified in the Arteriviridae family. Members of this family are small, cytolytic, positive-stranded, enveloped …
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Nuclear Transfer With Porcine Embryonic Stem Cells
… development of NT embryos constructed from porcine ES cells beyond the four-cell stage. However, enucleated zygotes supported development of NT embryos beyond the four-cell stage to the compact morula stage. These results provide preliminary evidence for in vitro development of NT embryos …
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Characterization of porcine adipose tissue-derived stem cells
… have not been identified in stem cells from porcine adipose tissue, an easily attainable tissue resource. The phenotypic profile of cell surface proteins and chromosomal stability of porcine adipose tissue-derived stem cells (pASCs) through in vitro culture have not been described. Also, …
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Pseudorabies Virus Infection of Porcine Peripheral Blood Leukocytes
Pseudorabies virus (PRV) is an alphaherpesvirus of swine that causes significant morbidity in adult populations, morbidity and mortality in young pigs, and economic losses to the swine industry each year. Evidence suggests that PRV causes immunosuppression in infected swine with resultant risk of …
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Immune modulation mechanisms of porcine circovirus type 2
Porcine circovirus associated disease (PCVAD) is an umbrella term for a multitude of diseases and syndromes that have a negative impact on the health and economics of pig production operations throughout the world. Porcine circovirus type 2 is the causative agent of PCVAD; however the presence of …
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Expression of recombinant porcine preprorelaxin in Nicotiana tabacum
… of this research was to express fully processed porcine relaxin in transgenic tobacco plants, as an alternative to current methods of producing relaxin. Two recombinant relaxin genes were constructed that contained the patatin signal peptide cDNA fused in frame to prorelaxin cDNA, which was …
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Pathogenic effects of Mycoplasma hyopneumoniae on porcine tracheal organ cultures and neutrophils in vitro, and porcine respiratory goblet cells in vivo
… calcium flux was examined after incubation of porcine neutrophils with or without M. hyopneumoniae. After zymosan stimulation, intracellular calcium levels were significantly increased in neutrophils incubated with M. hyopneumoniae. Enhancement of the zymosan-induced intracellular calcium flux …
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Development of Virus-like particles (VLPs) Based Vaccines Against Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Porcine Epidemic Diarrhea Virus (PEDV)
Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine epidemic diarrhea virus (PEDV) are two of the most prevalent swine pathogens that have impacted the global swine industry for decades. Both are RNA viruses with increasing heterogeneity over the years, making a vaccine solution …
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