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Showing 1 to 1 of 1 for “"Polysome-profiling, SNPs, allelic imbalance, mRNA translation"”.
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Mining common genetic Variants impacting on Allele-Specific Translation and cancer risk
The mRNA translation regulation is a critical factor in protein expression and cellular homeostasis, with deep implications for cancer biology. The work described in this thesis identifies, validates, and investigates allele-specific differences in translation efficiency mediated by tranSNPs: …