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Showing 1 to 20 of 397 for “"Polysaccharide"”.
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Immunologic Memory to Polysaccharide Antigens
… elicit memory B cells, it is not known whether polysaccharide antigens do. Here we report that polysaccharide antigens elicit memory B cells that are phenotypically distinct from those elicited by protein antigens. We show that antigen affinity of the B cell receptor regulates the development of …
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Force-extension of the Amylose Polysaccharide
Myasthenia gravis (MG) is an autoimmune disorder in which auto-antibodies directed at the acetylcholine receptors (AChR) of the neuromuscular junction (NMJ) block, alter or destroy their targets. The anti-AChR antibodies cause activation of the classical complement pathway leading to inflammatory …
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Regioselective Synthesis of Polysaccharide-based Polyelectrolytes
Polysaccharides are one of the most abundant and diverse families of natural polymers, and have an incredibly wide range of natural functions including structural reinforcement, energy storage, aqueous rheology modification, and communication and identity. Application of native polysaccharides like …
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Adsorption of Biomacromolecules onto Polysaccharide Surfaces
Plant cell wall polysaccharides are abundant natural polymers making them potential sources for sustainable and biodegradable materials. Interfacial behavior, including adsorption and enzymatic degradation, of several plant cell wall polysaccharides and their derivatives were studied with a quartz …
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Polysaccharide-Based Nanocarriers for Improved Drug Delivery
… for selective accumulation in the diseased area. Polysaccharides are non-toxic and biodegradable natural polymers that can serve as the basis for these nano-sized carriers. Polysialic acid (PSA) is such a polysaccharide with strong hydrophilicity that may reduce uptake by the reticuloendothelial …
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Grewia polysaccharide gum as a pharmaceutical excipient
… the storage site by extraction processes. Grewia polysaccharide gum was extracted and dried using techniques such as air-drying, freeze-drying or spray-drying. Component analysis of the gum showed that it contains five neutral sugars: glucose, galactose, rhamnose, arabinose and xylose. The gum …
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Studies on Polysaccharide Synthesis and Solution Behavior
To better understand the interaction of water with hyaluronan, two uronic acids, beta-methyl glucuronic acid and beta-methyl galacturonic acid, were prepared, and their hydroxyl protons were studied using low temperature NMR. These results were compared to calculations of proton exchange in uronic …
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Regioselective Design of Polysaccharide Ester Graft Copolymers
Polysaccharide graft (co)polymers, where a polysaccharide comprises the backbone and a separate (co)polymer comprises grafted side chains, are growing in popularity as blend compatibilizers, sustainable elastomers, self-assembling materials, and drug delivery components. This popularity is …
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Adsorption of Blood Proteins onto Polysaccharide Surfaces
… (HSA) and human serum fibrinogen (HSF), on two polysaccharide materials used for hemodialysis membrane applications: regenerated cellulose and cellulose acetate. The study aims to provide insight into the design of novel hemocompatible polysaccharide materials. Information such as real-time …
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COMPLEX FORMATION BY ALPHA-LACTALBUMIN AND POLYSACCHARIDE COPOLYMERS
… Complexes formed among proteins and polysaccharides, as renewable biopolymers, are drawing attention for their potential application in the food, pharmaceutical, and cosmetic industries due to their non-toxicity and higher potential for rapid biodegradation.
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Pathways for Biosynthesis of a Bacterial Capsular Polysaccharide
Made available in DSpace on 2014-12-05T21:45:32Z (GMT). No. of bitstreams: 1 6000245.pdf: 4026261 bytes, checksum: 27b3d6f07849fe12ed2e253b6ff2f939 (MD5) Previous issue date: 1959
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Engineering chemoattractant gradients using controlled release polysaccharide microspheres
… chemoattractant secreting cells using cell-sized polysaccharide-based hydrogel microspheres releasing chemoattractant in a controlled manner. These alginate hydrogel microspheres, ~30 [mu]m in size, were crosslinked with Ca2+ between gluronic acid units on alginate backbones and provided a natural …
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Synthesis of Polysaccharide-based Biomaterials for Drug Delivery
Synthetic strategies for polysaccharide-protein conjugates, pH-responsive hydrogels, and amorphous solid dispersion (ASD) polymers were developed. Conjugating a polysaccharide to a protein drug via a covalent bond may improve its medical properties including solubility, stability, immunogenicity, …
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Design Of A Polysaccharide Derived Tissue Engineered Vascular Graft
<p>DESIGN OF A POLYSACCHARIDE DERIVED TISSUE ENGINEERED VASCULAR GRAFT</p> <p>By</p> <p>Irina Robu</p> <p>November 2010</p> <p>Advisor: Dr. Howard Matthew</p> <p>Major: Chemical Engineering</p> <p>Degree: Doctor of Philosophy</p> <p>As the most frequent congenital anomaly and the leading cause of …
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Investigation of storage polysaccharide metabolism in lactic acid bacteria
Das Polysaccharid-Glykogen ist aus vielen Bakterien wie auch Eukaryoten bekannt. Es enthält ausschließlich über α1-4 Bindungen verknüpfte Glucoseeinheiten, die über α1-6-Bindungen verzweigt sind. Generell ist es als ein Speichermolekül anzusehen, das sowohl Kohlenstoff- als auch Energiequelle unter …
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Recombinant production and regioselectivity study of lytic polysaccharide monooxygenases
… breakthrough came with the discovery of lytic polysaccharide monooxygenases (LPMOs). These enzymes oxidatively cleave and disrupt the ordered structure of cellulose, making it better accessible for classical cellulases. Therefore, these enzymes are currently attracting much scientific …
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RNA regulation of polysaccharide metabolism in human gut Bacteroidetes
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Structural studies on enzymes involved in uronic acid polysaccharide degradation
… heparin sulfate, hyaluronan etc.,) and cell wall polysaccharides of plants (pectate/ pectin) and marine algae (alginate, ulvan). Glycosaminoglycans (GAGs) participate in a variety of cellular functions including stabilization of the extracellular matrix, control of hydration and organism …
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Tolerant effect of type 111 pneumococcal capsular polysaccharide in rabbits
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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