Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Polymeric Microparticles"”.
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Development and characterisation of photosensitiser-incorporated polymeric microparticles
… of a range of photosensitiser (PS)- incorporated polymeric microparticles, optimising the photodynamic antibacterial activity exerted. Specifically, their ability to reduce the bacterial bioburden of solutions, with low visible light illumination, was studied. An oscillatory ball milling process …
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Characterization of Biodegradable Polymeric Microparticles for Controlled Release
The formation of microcapsules is a complex process relying on thermodynamic, kinetic and other factors such as the physical drug. Continued study in the microparticle arena will help achieve better control of release and allow for application of more potent therapeutics.
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Development of Binary Composite Solid Microparticles for Improved Intranasal Absorption of Low Permeation Drug Molecules
… states that preparation of binary composite microparticles with Pluronic® triblock copolymers (polyethylene glycol-polypropylene glycol-polyethylene glycol) should allow increased drug transport across nasal mucosal tissue relative to drug alone. Testing the hypothesis necessitated execution …
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Microfluidic approaches to the synthesis of complex polymeric particles
The synthesis of micron-sized polymeric particles with precise control over shape, monodispersity and chemistry is a technologically important objective. Varied applications including medical diagnostics. designer fabrics and optical devices could benefit from the availability of geometrically …
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Fabrication, dynamics and self-assembly of anisotropic colloidal particles
… work, we study the fabrication and behavior of polymeric microparticles that are chemically- and shape-anisotropic. Single-component, rod-shaped particles are fabricated by stop-flow lithography (SFL) using either hydrophobic and hydrophilic materials. SFL is also used to fabricateJanus …
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Controlled synthesis of magnetic particles
… addition, we synthesized non-spherical magnetic microparticles with multiple functionalities, shapes and chemistries. Particle synthesis is performed in two steps; polymeric microparticles homogenously functionalized with carboxyl groups were generated AA % using stop-flow lithography, and then …
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Colloid phenomena in surface-modified polymer systems.
… layers. A new method for the modification of polymeric microparticles has been proposed. A technique for the production of micro-patterned surfaces has been developed. The resulting changes can be effectively studied and understood using the techniques applied. AFM and XPS have been used to …
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Elucidation of Drug Release Mechanisms in PLGA Microspheres
… model for predicting drug release from polymeric microparticles. We demonstrated the applicability of the code as a tool to account for drug release governed by diffusion as well as degradation and erosion. The key benefit to the code is its adaptability. Whereas most models for drug …
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Microfluidic synthesis, characterization, and applications of bioinspired deformable microparticles
Polymeric microparticles have a wide variety of uses, ranging from traditional applications in paints and coatings, to specialized applications in medical therapeutics and diagnostics. For biological applications - including drug delivery, analytical assays, and tissue engineering - it is important …
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Drug delivery systems to include liposomes and microparticles in order to aid treatment of glioma.
… manifest toxicity. The effects of liposomes and polymeric nanoparticles in cancer chemotherapy have been investigated in recent years and there have been some interesting outcomes resulting in improved survival rates of the patients. Thus, the present study was carried out to investigate the …
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Anti-inflammatory drugs for modulation of host response to biomaterials and application in diabetes therapy
… drug formulation. Poly-lactic-coglycolic (PLGA) microparticles with low loading (1.3wt%) of dexamethasone locally inhibited the activity of cathepsin enzymes from immune cells, while high drug loading formulation (26wt%) resulted in systemic immunosuppression. We also showed that incorporation of …
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Microfluidic processes to create structured microparticle arrangements and their applications
Multifunctional polymeric microparticles have shown the great potentials in a variety of fields. While the advance in particle synthesis allows for fine tuning of their physical properties and chemical functionality, particle manipulation is still appealing, but challenging issue in colloidal …
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Stop-flow lithography for complex particle synthesis and application in directed assembly
The synthesis of complex microparticles is an important objective. These particles can find use in a number of applications ranging from tissue engineering to ceramics and assembly. Tuned assembly of anisotropic particles can give rise to macrostructures with complex morphologies. Externally …
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Rational design of microparticles for enhanced fragrance delivery
… laundry products: 1. Fragrance loading in microparticles can prevent premature release of the fragrance and adverse interactions between the fragrance and other ingredients in a product formulation both during storage and during the application process. 2. Fragrance adsorption onto a …
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The Encapsulation and Release of Flutamide Using Poly (ε-Caprolactone) Microspheres
… release delivery systems using non-toxic polymeric microspheres. These polymeric microspheres encapsulate the active agent improving its bioavailability and compliance, reducing drug toxicity and side effects. The aim of this investigation was to develop a controlled release FLT delivery …