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Showing 1 to 3 of 3 for “"Polymerase-Protein"”.
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Cellular functions and enzymatic activity of the poly(ADP-ribose) polymerase protein family
The poly(ADP-ribose) polymerase (PARP) protein family consists of seventeen enzymes and generates ADP-ribose (ADPr) posttranslational modifications onto target proteins using NAD* as a substrate. While functions for PARPs in the nucleus, such as in DNA damage repair and transcriptional regulation, …
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Mechanismus der Polymerase-Inkorporation in foamyvirale Partikel
… mit Ausnahme der Foamyviren (FV), wird das Pol-Protein als Gag-Pol-Fusionsprotein exprimiert. Dieser Mechanismus sichert die Inkorporation von Pol in das virale Partikel. FV unterscheiden sich in vielen Merkmalen von den Orthoretroviren, unter anderem wird das Pol-Protein von einer eigenen …
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Solution Conformations and Structural Thermodynamics of Type I DNA Polymerases from Escherichia coli and Thermus aquaticus
The global conformations of DNA polymerase I from Thermus aquaticus (Taq/Klentaq) and E. coli (Pol I/Klenow) both in isolation and in complex with DNA have been examined in solution using hydrodynamic (analytical ultracentrifugation) and small/wide angle X-ray scattering techniques and then …