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Showing 1 to 1 of 1 for “"Polymerase substitution."”.
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DNA polymerase interactions and their role In translesion synthesis substitutions.
… to continue after a high fidelity (HiFi) polymerase stalls at a lesion. Upon stalling, the HiFi polymerase must be substituted with a TLS polymerase. The reverse substitution must occur promptly after lesion bypass to minimize error-prone synthesis by TLS polymerases opposite undamaged DNA …