Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 24 for “"Polycystic Ovarian Syndrome"”.
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A Review to Critique the Literature on Polycystic Ovarian Syndrome Origins
<p>Polycystic Ovarian Syndrome (PCOS) is a complex disorder found in 5-10% of women of reproductive age. The disorder affects hormone levels and reproductive abilities in part by altering follicular development in the ovary. The disorder is a major cause of infertility in women. PCOS has been …
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The Association of Adipokines and Insulin Resistance in Women with Polycystic Ovarian Syndrome
… increasing concern to premenopausal women is Polycystic Ovarian Syndrome (PCOS). PCOS leads to numerous health-related concerns, including insulin resistance. The cause of insulin resistance in women with PCOS is unknown, but adipokine levels may play a role. PURPOSE: The primary purpose of …
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The impact of obesity and fitness on endothelial function in polycystic ovarian syndrome
Polycystic ovarian syndrome (PCOS) is a highly prevalent heterogeneous syndrome associated with abdominal obesity, insulin resistance and the metabolic syndrome. This clustering of risk factors could translate into an adverse cardiovascular disease (CVD) risk profile. Endothelial dysfunction, an …
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Polycystic Ovarian Syndrome: An Investigation of Non-Pharmacologic Management Strategies and Cardiometabolic Consequences
… and psychosocial health in women with polycystic ovary syndrome (PCOS).Objective: To evaluate the effects of exercise training on reproductive, anthropometric, cardiometabolic, and sleep quality health measures in reproductive-aged women with PCOS.Methods: First, we performed a …
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Study of intuitive eating ratings and self-efficacy differences in women with Polycystic Ovarian Syndrome (PCOS)
<p><strong>Background</strong>: Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder, which if left untreated can lead to infertility and diabetes.</p> <p><strong>Objective</strong>: To determine whether women with PCOS who practice intuitive eating skills are more confident in sustaining …
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Life After Menopause: Quality of Life in Women Diagnosed With PolyCystic Ovarian Syndrome After The Childbearing Years
<p>Very little research has been conducted in regards to what happens after a woman diagnosed with PCOS is menopausal or post menopausal. This study researched the quality of life in women with PCOS before and after menopause in an attempt to compare the two groups.</p>
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Public health nutrition intervention to enhance healthy eating and lifestyle modification among Lebanese women with Polycystic Ovarian Syndrome
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy disorder in reproductive age women. The symptoms of this disorder are the androgen excess seen with anovulation/oligoovulation or morphologically ovarian cysts. The aim of the study was to assess the efficacy of public health …
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Being an Ally: Communication Design's Role in Improving the Health Information Seeking Experience in People with Polycystic Ovarian Syndrome
… people assigned female at birth have PCOS (Polycystic Ovarian Syndrome). It is very likely that most people have or will have a relationship with someone that has PCOS. It is a complicated, difficult to treat, underfunded, chronic health condition. People with PCOS struggle to get diagnosed, …
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Modeling Pathophysiology of Human Fallopian Tube Using Microfluidic Organ-on-Chip Technology
Ovarian cancer is a deadly disease, and most high-grade serous ovarian carcinomas originate from the fallopian tube epithelium. Understanding the early events of ovarian cancer tumorigenesis in the fallopian tube is crucial for the development of future detection and intervention strategies. This …
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Progesterone Receptor Regulation of the Gene Networks That Control Ovulation in Mice
… releasing a fertilizable egg from a mature ovarian follicle. Although ovulation is a physiologically well-characterized event, the underlying molecular processes remain poorly understood. Based on research performed over the past twenty years, the steroid hormone progesterone, which exerts …
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Expression of DIO2 in the Porcine Ovary and the Granulosa Cells of Humans
… are production of gametes and steroidogenesis. Ovarian follicles are the functional component of the ovary and respond to hormonal changes in the body during reproductive cycles. As follicles develop, the somatic cells of the ovary differentiate into granulosa cells and theca cells. Following a …
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MULTISCALE TECHNOLOGIES FOR ENGINEERING AND CRYOPRESERVING OVARIAN TISSUES AND HUMAN IPSCs
… of the tightly controlled process of ovarian follicle development. Impaired fertility can arise from disorders like polycystic ovarian syndrome (PCOS) or premature ovarian insufficiency (POI), which affect the function of the ovary, an integral reproductive organ that houses the …
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Progesterone receptor targets play critical roles in maintaining pregnancy and disease prevention
The ovarian hormone progesterone influences many facets of uterine physiology through the transcriptional activity of progesterone receptor (PR). This body of work investigates the role of progesterone receptor targets heart and neural crest derivatives expressed 2 (HAND2) and insulin receptor …
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EGFR Signaling Is Necessary for Gonadotropin-Induced Steroidogenesis and Oocyte Maturation
… luteinizing hormone (LH) surge triggers ovarian processes that are critical for normal female fertility, including steroidogenesis, oocyte maturation, and subsequent ovulation. Studies were designed to examine the LH-induced signaling pathways that regulate ovarian steroidogenesis, as …
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Hormonal regulation of microRNA expression in the ovary
… understanding the transcriptional regulation of ovarian gene expression and how this relates to reproductive function. Recently, attention has turned to alternative forms of gene regulation, including post-transcriptional gene regulation. One mechanism of post-transcriptional gene regulation is …
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Endocrine markers of ovarian function: Clinical and biological aspects with focus on Anti Müllerian hormone
… closely related to female fertility is the ovarian reserve, a term used to designate both quantitative as well as qualitative aspects of the remaining gametes in the female gonads. Despite a natural age-dependent decline in terms of the amount of gametes, a substantial variability exists …
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The Hormonal Regulation of the Claudin Genes in the Ovary
… When these hormonal signals are disrupted, ovarian dysfunction can occur. One such example is Polycystic Ovarian Syndrome (PCOS). PCOS patients suffer from high levels of testosterone. Excess testosterone may misregulate genes in the ovary and disrupt ovarian function. The Claudin …
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Progesterone Regulation of the GnRH Pulse Generator
… reproductive and metabolic disorders, such as polycystic ovarian syndrome (PCOS).
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Interventions in patients at high cardiovascular risk
… pathological conditions such as type 2 diabetes, polycystic ovarian syndrome (PCOS) and hypopituitarism. Therefore, interventions in these patients at high risk of cardiovascular disease can be potentially beneficial to improve cardiovascular health and this is explored in the different chapters …
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Using human genomics to decipher biological mechanisms underlying reproductive ageing and fertility in women
Women are born with a non-renewable ovarian reserve, which is depleted throughout reproductive life. When this reserve is exhausted, they experience menopause and cease ovulating. Importantly, menopause timing is highly variable and can impact health outcomes in later life. One in 100 women …
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