Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Polycyclic compounds."”.
-
Studies directed toward the synthesis of optically active polycyclic compounds
Contains fulltext : mmubn000001_250112256.pdf (Publisher’s version ) (Open Access)
-
Explorations with Polycarbocyclic Cage Compounds
… rearrangements of this new cage dione to novel polycyclic systems were observed and subsequently were investigated. The structures of the new systems thereby obtained were determined unequivocally by application of X-ray crystallographic methods. It is noteworthy that the reactions reported …
-
Strategies and Tactics for the Synthesis of Polycyclic Alkaloids
… comprises one of the most ornate collections of polycyclic alkaloids known. The structural characterization of their unique scaffolds was accomplished through elegant spectroscopic studies. Furthermore, the synthesis of these alkaloids has attracted the attention of the synthetic community, with …
-
Synthetic Studies in the Formation of Nitrogen Containing Compounds: From Simple Amines to Complex Natural Products
Small nitrogen containing compounds are important building blocks in synthetic chemistry. Not only for biologically active small molecules but in more complex biologically active natural products. Having novel methods to access these types of molecules is an important undertaking in synthetic …
-
Antibiotics that Inhibit 30S or 50S Ribosomal Subunit Formation: Hygromycin B, Quinupristin-Dalfopristin and XRP 2868.
<p>Several antibiotics that prevent translation by binding to ribosomal subunits have been shown to also inhibit ribosomal subunit assembly (Champney and Tober 2003). The aminoglycoside hygromycin B was examined in <em>Escherichia coli</em> cells for inhibitory effects on translation and ribosomal …
-
Chemoselective and Stereoselective Exploration of the Chemical Reactivity Space of Castagnoli-Cushman-Derived Allylic Lactamoyl Esters: Application to the Synthesis of Aza-Polycyclic Architectures
The synthesis and evaluation of structure-activity relationships of saturated nitrogen heterocycles is the focal point of various pharmaceutical companies thanks to the high biological activity of previously isolated azacycles. Here, we describe an operationally simple and highly efficient approach …
-
A Diversity-Oriented Synthesis Approach to Functionalized Azaheterocycles using Cyclic Alpha-Halo Eneformamides
… cyclic propargylic and homoallylic amines, polycyclic lactams, as well as chiral dihydro 1,4-oxazines and thiazines. Given the generality of the approach, we are confident that the synthesis and medicinal chemistry communities will undoubtedly embrace it, thus, endowing it with a practical …