Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 47 for “"Polycaprolactone (PCL)"”.
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Characterization and development of polycaprolactone (PCL)/montmorillonite (MMT)/hydroxapaptite (HA) nano-composites for fused deposition modelling (FDM) process
… Deposition Modelling (FDM) was investigated. The polycaprolactone (PCL) filled montmorillonite (MMT) and Hydroxyapaptite (HA) composites were prepared by melting and compounding using a single screw extruder. The mechanical properties were assessed by tensile, flexural and charpy impact tests …
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Tailoring electrospun nanofibers and electrosprayed nanoparticles to enhance cellular uptake of low bioavailability drugs
… polymer polyvinylpyrrolidone (PVP), and polycaprolactone (PCL) were used in the projects to produce nanomaterials using simple and straight forward techniques of electrospinning and electrospraying. In the first project, preparation, and characterization of PCL and PVP nanoparticles, …
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Design and development of desktop fiber and fabric manufacturing system for advanced materials
… 3 layer fiber with Polystyrene (PS) cladding, Polycaprolactone (PCL) layer, and PS core. These fibers were used for neural probing and cell scaffold.
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Dissolution and Biokinetics of PCL in Denitrification Systems
This thesis investigates the potential of polycaprolactone (PCL), a biodegradable polymer, as a sustainable solid-phase carbon source for wastewater denitrification. Laboratory experiments examined the effects of temperature, bead mass, solvent type, hydraulic retention time, and bead reuse on PCL …
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DEVELOPMENT OF BIO-ACTIVE FOOD PACKAGING FILMS
… packaging films was developed by melt blending polycaprolactone (PCL) with chitosan as carrier for grapefruit seed extract (GSE). The influence of molecular weight (MW) of chitosan on the blend was investigated. Lower MW chitosan accelerated the release of GSE that led to significant improvement …
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FABRICATION AND CHARACTERIZATION OF CELL-LADEN 3D PRINTED HYBRID SCAFFOLDS FOR ESOPHAGEAL TISSUE REPAIR
… of electrohydrodynamic jet printed (E-jetted) polycaprolactone (PCL) / Pluronic F127 (F127) fiber mesh, and a layer of electrohydrodynamic sprayed (E-sparyed) printed PCL film, has been applied for esophageal TE application. The E-jetted fiber mesh includes controlled and regular structure with …
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3D Printing Of A Biocompatible Scaffold And A Real-Time Imaging Window For Monitoring Rat Spinal Cord Regeneration
… visualization. Candidate scaffold materials- polycaprolactone (PCL), poly(lactic-co-glycolic acid) (PLGA), and silicone- were evaluated to balance mechanical compliance with biological performance. While PLGA exhibited favorable mechanical characteristics, PCL demonstrated superior …
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Developing a labview based thermally stimulated current (tsc) controller to measure residual charge in electrospinning
… nanofiber mat. Using this technique electrospun PolyCaproLactone (PCL) mats are analyzed before and after immersion in culture media and Phosphate Buffer Solution (PBS) for 1, 4 and 7 days.
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Supercritical CO2 foamed biodegradable polymer blends of polycaprolactone and Mater-Bi.
… CO2 so blended with another polymer which is. Polycaprolactone is a biopolymer with potential of 4000% change in volume with CO2. Thus we investigate blends of Mater-Bi (MB) and polycaprolactone (PCL) foamed in supercritical CO2 using the batch process. Characterization of the foamed and …
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Coaxial Electrospinning of Synthetic/Natural Polymer Combinations for Controlled Release of Active Components in Biomedical Applications
… and structural properties. Specifically, polycaprolactone (PCL) as a shell layer demonstrates sustained prolonged release of active components while gelatin as the shell layer facilitates instant release. These findings underscore the versatility and efficacy of coaxial electrospinning in …
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Encapsulation of nanomagnetite within polycaprolactone microspheres for bone replacement
… combining magnetite nanoparticles with polycaprolactone (PCL) to produce a material that can soften in response to the application of an alternating magnetic field. The magnetite nanoparticles were synthesized by a non-surfactant method and then emulsified with PCL. Particle size …
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A microfabricated 3-D stem cell delivery scaffold for retinal regenerative therapy
… in vitro a novel ultrathin 3-D device made of polycaprolactone (PCL) for retinal cell replacement synthesized by the stacking, aligning, and bonding of three uniquely designed layers.
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A tissue-engineered approach to hernia repair
… mesh (drug-loaded polymeric mesh). Solutions of polycaprolactone (PCL) or polylactic acid (PLA), two aliphatic polymers commonly used in various clinical applications, were individually mixed with irgasan (IRG) (an antibacterial agent) or levofloxacin (LEVO) (a broad-spectrum antibiotic). Type I …
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A novel osteochondral composite consisting of a self-assembling peptide hydrogel and 3D printed polycaprolactone scaffold : potential for articular cartilage repair
… with an interconnected porous 3D printed polycaprolactone (PCL) scaffold to create a novel osteochondral construct. The self-assembling peptide hydrogel has been shown to provide an environment that maintains chondrocyte phenotype and viability. Furthermore, the 3D scaffold fosters …
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Effects of Therapeutic Radiation on Polymeric Scaffolds
… therapeutic radiation on three porous scaffolds: polycaprolactone (PCL), polyurethane (PU) and gelatin. Porous scaffolds were fabricated using solvent casting and/or salt leaching techniques. Scaffolds were placed in phosphate buffered saline (PBS) and exposed to a typical cancer radiotherapy …
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Characterization and modification of carbon composite electrodes towards more affordable biosensing applications and integration into fluidic devices
… into fluidic devices. Chapter 2 introduces polycaprolactone (PCL) as a new binder material for TPEs and focuses on the electrochemical characterization of the new material. The PCL-based TPEs have excellent electrochemical activity towards a wide range of analytes as well as high electrical …
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Development And Application Of Biomimetic Electrospun Nanofibers In Total Joint Replacement
… of coaxial electrospun NFs composed of polycaprolactone (PCL) and polyvinyl alcohol (PVA) polymers arranged in a core-sheath shape. The PCL/PVA NFs are biocompatible and biodegradable with appropriate fiber diameter, pore size and mechanical strength, leading to enhanced cell adhesion, …
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Advanced Electrohydrodynamic Atomisation Engineered Microneedle Coatings
… were assessed consisting of 5% w/v of polycaprolactone (PCL) in dichloromethane (DCM) and 5% w/v polyvinylpyrrolidone (PVP) in ethanol. A full factorial Design of Experiments (DoE) was used to assess the various parameters (applied voltage, deposition distance and flow rate). Further …
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Studies investigating the preparation of solid core drug delivery systems for oral delivery of y-globulin via supercritical fluid processing technology
… experiments involving particles formulated using polycaprolactone (PCL) and Eudragit® S100 (ES100), and commercially obtained silica known as MSU-H, Syloid AL-1 FP (SAL), Syloid XDP-3150 (SXDP), and Syloid 244 FP (SFP). For silica particles, protein adsorption followed the descending trend of SFP …
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Bioresorbable Osmotic Pump for Long–term Contraception
… non-solvent induced phase separation method with Polycaprolactone (PCL) and achieved acceptable molecular weight cut-off values around 50-100k Da. Hyaluronic acid was selected for the osmotic engine, and our early work confirmed its potential for linear expansion and for overcoming the high …
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