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Showing 1 to 2 of 2 for “"PolyIC"”.

  1. Exploring the immunologic consequences of ATRX deficiency in glioma

    … increased innate immune signaling in response to PolyIC agonism and STING agonism, which was observed at the protein level, RNA level, and functional level via cytokine expression. The observed increase in immune signaling was dampened by IDH-mutation, and inhibition of mutant IDH relieved this …

    uthsc Repository record for Exploring the immunologic consequences of ATRX deficiency in glioma (opens in a new tab)

  2. Regulation of The Expression and Lysine Acetylation of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (LPCAT2) in RAW264.7 Cells

    Lysophosphatidylcholine Acyltransferases (LPCATs) are Lipid modifying enzymes that significantly regulate changes in the glycerophospholipid components of the macrophage membrane phospholipid bilayer. LPCAT2 is a subtype of LPCAT that regulates inflammatory responses to infection by …

    plymouth Repository record for Regulation of The Expression and Lysine Acetylation of Pro-Inflammatory Molecules By Lipid-Modifying Enzyme (LPCAT2) in RAW264.7 Cells (opens in a new tab)