Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Poly-Proline"”.
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Enantio-Selective Mechanism of the Poly-Proline Chiral Stationary Phase: a Molecular Dynamics Study
Poly-proline-based chiral stationary phases are relatively new stationary phases and have shown to be competitive to other commercially available chiral stationary phases for high performance liquid chromatography (HPLC). The conformational studies, solvation properties and enantio-selective …
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The role of a highly conserved eubacterial ribosomal protein in translation quality control
… established function is in the translation of poly-proline containing proteins. EF-P deficient cells were nearly inviable in the absence of L9; however, L9 did not directly influence poly-proline translation. Therefore, in each case, L9 improved cell health without altering the activity of …
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Processive Acceleration of Actin Barbed End Assembly by N-WASP
… the actin cytoskeleton. N-WASP activated actin polymerization drives extension of invadopodia and podosomes into the basement layer. In addition to activating Arp2/3 complex, N-WASP binds actin filament barbed ends, and both N-WASP and barbed ends are tightly clustered in these invasive …
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The Development of a New Cloning Strategy for the Biosynthetic Production of Brush-Forming Poly(Amino Acids)
The design and discovery of new surface-active polymers that self-assemble on solid substrates to form brush layers will have a major impact on numerous applications. Through recombinant DNA technology, there exists the potential to harness a cell's protein synthesis machinery to produce a …
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Development of New Synthetic Approaches to Biologically-Active Peptides
… molecules was investigated. Fluorinated prolines were used to explore protein-protein interactions and dynamics, specifically to study the peptidyl-prolyl isomerase cyclophilin D (CypD). First, short substrates were synthesised, including a section of Bcl2 (8 amino acids) and F0F1 ATPase …