Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Poly (c) binding"”.
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MicroRNA-122 and Poly(C)-Binding Protein 2 Bind to the Hepatitis C Virus Genome, Regulating Viral Replication and Genome Structure
… the host factors, microRNA-122 (miR-122) and poly-(C) binding protein 2 (PCBP2), may regulate these two processes. These host factors promote HCV replication and compete for overlapping binding sites on the 5’ untranslated region (UTR) of the HCV genome. This work investigates how miR-122 and …
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Structural Basis For Poliovirus Cloverleaf-Mediated Regulation Of Genome Replication
… product 3CD (a fusion of 3C protease and 3D RNA polymerase) and host-protein Poly-C binding Protein 2. The formation of this complex is critical for the initiation of negative-strand RNA synthesis. In order to investigate the function and role of the cloverleaf, we report the X-ray crystal …
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Effects of DFO-Induced Hypoxia on Key Signaling Mediators
… interacting with the transcription regulator Poly C Binding Protein (PCBP-1), can negatively regulate MOR gene expression using a yeast two-hybrid screening system. RT-PCR analysis revealed an increased in RACK-1 expression while a decrease in MOR expression under DFO treatment was observed. …