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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Poly(ethylene glycol) (PEG)"”.
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Structure and Dynamics of Polyhedral Oligomeric Silsesquioxane (POSS) and Poly(Ethylene Glycol) (PEG) Based Amphiphiles as Langmuir Monolayers at the Air/Water Interface
Throughout the study of polymeric Langmuir monolayers at the air/water (A/W) interface, the Wilhelmy plate and Langmuir-Blodgett (LB) techniques along with Brewster angle microscopy (BAM) have been identified as key methods for acquiring structural, thermodynamic, rheological and morphological …
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Diels-Alder Reactions of 5-[Methoxypoly(Oxyethylene)]-(3E)-1,3-Pentadiene
Poly(ethylene glycol) (PEG) derivatives have wide utility for a variety of biomedical and biotechnical applications, and interest continues in the synthesis of new PEG derivatives that possess novel properties. In this work, we have performed the synthesis of …
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Doppelthydrophile Blockcopolymere als Mineralisationstemplate
… den Eigenschaften von doppelthydrophilen Blockcopolymeren und ihrer Anwendung in einem biomimetischen Mineralisationsprozeß von Calciumcarbonat und Bariumsulfat. Doppelthydrophile Blockcopolymere bestehen aus einem hydrophilen Block, der nicht mit Mineralien wechselwirkt und einem zweiten …
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A potential route to hydrogel multifunctionalization utilizing encapsulation of acrylate-conjugated streptavidin
… affinity. Streptavidin was conjugated to acryl-PEG-N-hydroxysuccinimide, a commercially available molecule that allows chemical binding to poly(ethylene glycol) (PEG) diacrylate and dextran acrylate hydrogels. Such gels were made by photocrosslinking solutions of APN and streptavidin conjugated …
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Inverse opal hydrogel scaffolds as lymphoid microenvironments for the study of immune cell migration and immunotherapy
… We developed and tested macroporous poly(ethylene glycol) (PEG) hydrogel scaffolds as a platform for lymphoid tissue models and immunotherapy. By applying the method of colloidal crystal templating to materials and length scales appropriate for soft tissues, PEG hydrogels with arrays …
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Characterizing hydrogel imposed strain fields on brain tissue phantom for use in neural implant device coatings in presence of micromotion
… This study investigated the effects of poly(ethylene glycol) (PEG) hydrogel coatings for glass brain implant devices on strain fields imposed by those devices to brain tissue due to micromotion in the brain. PEG hydrogels were created using macromers of 2000-8000 Mw and 5-20 wt.% in …
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Design and Synthesis of Doxorubicin Conjugated Gold Nanoparticles as Anticancer Drug Delivery System
… evaluated. These doxorubicin analogs and the poly(ethylene glycol) (PEG) stabilizing ligands were conjugated to gold nanoparticles via formation of a gold-thiol bond. The systems were evaluated in vitro and in vivo, and the results show that controlled drug release can be achieved either by …
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Engineering Biosurfaces for Cell Studies
… the first study, protein and cell resistance of poly(ethylene glycol) (PEG) and oligo(ethylene glycol) (OEG)-terminated self-assembled monolayers (SAMs) were studied as a function of the chain length of the OEG unit. In general, PEG with high molecular weight is better than short OEG SAMs in …
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Factors Affecting Size and Swelling of Poly(ethylene glycol) Hydrogel Microspheres Formed in Aqueous Sodium Sulfate Solutions
… critical solution temperature: LCST) behavior of poly(ethylene glycol): PEG) in aqueous sodium sulfate solutions was exploited to fabricate hydrogel microspheres under mild conditions without the use of other monomers, polymers, surfactants or organic solvents. Reactive PEG derivatives underwent …
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Effect of cross-linking on the diffusion of water, ions and small molecules in hydrogels
… investigations of chemically-cross-linked poly(ethylene glycol) (PEG) hydrogels are reported with the aim of exploring the diffusion properties of water, ions, and rhodamine within the polymer at the molecular level. The water structure and diffusion properties were studied at various …
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Three dimensionally flocculated proangiogenic microgels for neovascularization
… of negatively charged microgels composed of poly(ethylene glycol) (PEG) microgels and poly(sodium acrylate), and positively charged microgels composed of PEG and poly(vinyl benzyl trimethyl ammonium chloride). The structural strength of the colloidal gel could be tuned with the zeta potential …
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Modular Nanoparticles for Selective Cell Targeting
… for selective cell targeting. Specifically, polyelectrolyte complexes composed of heparin (Hep, a growth factor binding glycosaminoglycan) and poly-L-lysine (PLL, a homopolymeric lysine) were prepared via a pulse sonication method. The Hep/PLL core NPs were further layered with additional …
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Ellipsoidal polyaspartamide polymersomes with enhanced cell-targeting ability
Nano-sized polymersomes functionalized with peptides are being increasingly studied for targeted delivery of diagnostic and therapeutic molecules. Earlier computational studies have suggested that ellipsoidal nanoparticles, compared to spherical ones, display enhanced binding efficiency with target …
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Development and Characterization of Reagent Pencils for Microfluidic Paper Based Analytical Devices
… on the molecular weight dependence, polymer chain end functionality, and polymer-graphite ratio was conducted to determine the most desirable parameters in reagent pencil composition. Further, the effects of enzyme stability in the presence of poly(ethylene glycol) (PEG) is …
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Multiscale modeling of thin film deposition processes
… the presence of three representative additives, poly ethylene glycol (PEG) and bis-(sodium sulfoprophyl) (SPS) and chloride. The proposed kinetic mechanism is capable of describing the synergistic effect of different additives on the copper deposition. Statistically designed experiments were …
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Enabling technologies for multiplexed biomolecule analysis and cell sorting
… consist of microbeads precisely patterned in poly(ethylene glycol) (PEG) matrices. Using microfluidics and projection lithography on a standard microscope, magnetically-active or protein-decorated beads were patterned in close-packed or disperse-bead patterns on glass substrates with high …
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Surface-Enhanced Raman Spectroscopy for Environmental Analysis: Optimization and Quantitation
… AuNP aggregation and subsequent coating of poly(ethylene) glycol (PEG). These nanoprobes were applied for pH detection in cancer cells and in phosphate buffered aerosol droplets. The latter experiments suggest that stable pH gradients exist in aerosol droplets.
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Improving Biocompatibility By Controlling Protein Adsorption: Modification And Design Of Biomaterials Using Poly(Ethylene Glycol) Microgels And Microspheres
… is described for the covalent attachment of poly(ethylene glycol): PEG)-based hydrogel coatings onto biomaterials surfaces for the minimization of protein adsorption. The coatings are applied using partially crosslinked PEG solutions containing polymer and protein oligomers and microgels that …
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Computational Modelling of Radiosensitising Properties of Nanoparticles
… any coated NP system. The detailed structure of poly(ethylene glycol) (PEG)-coated gold nanoparticles (AuNPs) was studied using atomistic classical molecular dynamics simulations. By varying the number of attached PEG molecules it was demonstrated that the thickness of the coating, and therefore …
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Enzymatic crosslinking of dynamic hydrogels for in vitro cell culture
… peptide ligation were established. Specifically, poly(ethylene glycol) (PEG)-peptide hydrogels were fabricated with peptide linkers containing pendent SrtA substrates. The hydrogels were stiffened through incubation with SrtA, whereas gel softening was achieved subsequently via addition of SrtA …
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