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Showing 1 to 1 of 1 for “"Poly(A)-Binding Protein I"”.
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The Role of the Human Nuclear Poly(A) Binding Protein in RNA Decay
… Here, I describe our work showing that polyadenosine (poly(A)) tails can stimulate transcript decay in the nucleus of human cells, a function mediated by the ubiquitous nuclear poly(A) binding protein PABPN1. We show that PABPN1 is required for the degradation of a viral nuclear …