Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Point-of-care (POC) diagnostic"”.
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The development of aptamer-based probes for the detection of TB antigens ESAT-6.CFP-10 potential TB diagnostic tools
Lack of point-of-care (PoC) diagnostic tools for TB hinders control of the disease, particularly in resource-limited, high HIV and TB prevalence countries. Therefore, there is a need for simple, rapid, accurate, and affordable PoC diagnostics to detect active TB early enough for opportune …
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Interferon-γ aptamers for the diagnosis of extra-pulmonary tuberculosis
… is a major global health problem. About 15-20% of the global population who are HIV negative have extra-pulmonary TB (EPTB) such as pleural TB. This increases to 50-70% in HIV positive people. The diagnosis of EPTB is challenging because of the low bacillary burden. Interferon gamma (IFN-γ) has …
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Operational Innovations to Improve Malawi’s HIV Sample Transportation Network
The African nation of Malawi, like other sub-Saharan countries, provides diagnostic testing to its citizens through a centralized laboratory network. Diagnostic samples are collected from patients at remote, point-of-care health facilities and diagnostic tests are performed at centralized …
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Spray coated bentonite/MWCNT composite enzymatic biosensor for uric acid detection
Biosensors are widely used in healthcare and diagnostics, offering rapid and reliable detection of biological analytes. This study presents the development of an enzymatic uric acid (UA) biosensor based on a nanocomposite of bentonite (BT) and multi-walled carbon nanotubes (MWCNTs) fabricated via …
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Development of an optical cavity-based biosensor for point-of-care diagnostics.
… using a differential detection method towards point-of-care (POC) diagnostic applications. The optical cavity consisting of two partially reflective surfaces with a small gap was designed and optimized using a simulation tool, FIMMWAVE/FIMMPROP. The optical cavity samples were fabricated in the …
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Electrostatic control of microfluidic systems for enhancement of nanoparticle separations and FET nanobiosensors
An abundance of ions in saline media or physiological buffers causes extensive shielding of charged surfaces and potentials. As a result, electrostatic forces cannot penetrate beyond the electrochemical double layer (EDL); conversely, charged molecules outside the EDL cannot transduce a sensor …
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Magnetic bead-based DNA extraction and purification microfluidic chip
… has been designed to be used for extraction of the target DNA molecules from whole blood sample. Mixing and separation steps are performed using functionalised superparamagnetic beads suspended in the cell lysis buffer in a circular chamber that is sandwiched between two electromagnets. …