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Showing 1 to 4 of 4 for “"Pnkp/Hen1"”.
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Probing substrate specificity of RNA repair protein Pnkp/Hen1 from Anabaena variabilis
… substrate specificity of a RNA-repair protein Pnkp/Hen1 from bacteria Anabaena Variabilis. Following the previous discovery of a RNA repair protein—Pnkp/Hen1, which can repair ribotoxin cleaved tRNA in vitro and can add a methyl group at the cleaved site to prevent further cleavage, this study …
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Biochemical and Structures Studies of tRNA Modificaton and Repair Enzymes
… at their 3' ends at the 2' OH position by Hen1, an S-Adomet dependent methyltransferase. Hen1 homologs in animals are shown to be responsible for the methylation of piRNAs, some siRNAs as well as endogenous siRNAs. Interestingly, a subset of bacteria also has a Hen1 homolog. Since bacteria …
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Discovery and characterization of novel RNA repair systems
… was found in T4phage, in which two proteins T4Pnkp and T4Rnl carried out RNA healing and sealing, respectively. The bacterial Pnkp/Hen1 complex has also been shown to repair ribotoxin-cleaved RNAs in vitro, but it was distinguished from T4 systems by performing 3’-terminal 2’-O-methylation …
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Biochemical and Structural Studies of RNA Modification and Repair
… RNA repair system composed of bacterial Pnkp and Hen1. Hen1 and Pnkp appeared pair-wise in the same operon in 39 of 934 bacterial species. Pnkp has been shown to have kinase, phosphatase, and adenylyltransferase activities, which are hallmarks of RNA repair. However, Pnkp alone is not …