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Showing 1 to 20 of 60 for “"Pluronic"”.
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The development of novel hybrid poly (2-oxazoline)-based bioinks for 3D bioprinting: a comparative study with Pluronic F127
… 3D bioprinting. Hybrid hydrogels consisting of Pluronic F127 (PF) and natural polymers have been suggested to have good printability and rheological behaviors. However, PF tends to be cytotoxic at concentrations required for good printability. Another synthetic copolymer which comprises …
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Flexible and Versatile Soft Templates for Mesoporous Silicas and Organosilicas Based on Pluronic Block Copolymer Surfactants and their Mixtures
… electron microscopy characterization of Pluronic surfactant templated nanotubes and 2-D hexagonal ordered mesoporous silicas based on tilt-series imaging at different angles. Chapter 3 shows the effects of stirring rate on fragmentation in silica nanotubes and the resulting nanosphere …
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Thermosensitive Injectable Pluronic Hydrogels for Controlled Drug Release: Characterisation of thermal, rheological and structural properties of injectable pharmaceutical formulations
… for injectable controlled drug delivery from Pluronics to enhance patients compliance, decrease side effects, reduce dose and frequency. A biocompatible copolymer, Pluronic F127 was probed as the main ingredient for the injectable systems owing its low gelation concentration and ease of …
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Thermosensitive Injectable Pluronic Hydrogels for Controlled Drug Release: Characterisation of thermal, rheological and structural properties of injectable pharmaceutical formulations
… for injectable controlled drug delivery from Pluronics to enhance patients compliance, decrease side effects, reduce dose and frequency. A biocompatible copolymer, Pluronic F127 was probed as the main ingredient for the injectable systems owing its low gelation concentration and ease of …
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The production of a lyotropic liquid crystal coated powder precursor through twin screw extrusion.
… crystal coated powder precursor by exploiting Pluronic F127 thermoreversible gelation property to get powder precursor without granular aggregates or with less compacted granular aggregates. The highly soluble chlorpheniramine maleate loaded in Pluronic F127 solution coated MCC particles …
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Fabrication of tissue engineering scaffolds with spatial control over architecture and cell-matrix interactions in 3D
… surface chemistry were fabricated by printing Pluronic® F 127. a surfactant molecule containing PEO chains, in selected locations. Spatial control of MG-63 cell adhesion and morphology was demonstrated on patterned PLLGA surfaces and porous scaffolds. Cell numbers were reduced on Pluronic® …
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Direct liquid crystal templating of mesoporous silica
… liquid crystal phases of the<br/>surfactants Pluronic PI23, Pluronic F127, CTAB and Brij 78. The factors affecting the<br/>regularity, morphology, pore diameter and wall thickness of the templated mesoporous<br/>silicas were examined by exploring the reaction composition space and plotting …
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Application of PEO-PPO-PEO Triblock Copolymers in Synthesis of Silica and Organosilica Nanomaterials
… the research work focused on the application of Pluronic triblock copolymers, poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO), in the synthesis of mesoporous material, such as double-helical silica nanotube structures as well as bridged organosilica nanotubes by …
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Carbogenic Nanoparticles for Biomedical Applications
… namely carbogenic nanoparticles or C-dots, to Pluronic® hydrogels.
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Cardiovascular Diseases Factors in Women Enrolled in the Wisewoman Program
… <p>At the nano scale, thermally responsive Pluronic F127 based nanocapsules using chitosan as the crosslinker were synthesized. The Pluronic F127-chitosan nanocapsules were found to have excellent biocompatibility, presumably due to the biocompatible nature of the two constituent polymers. …
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Synthesis and characterization of pH/temperature dual sensitive multiblock copolymer for drug delivery
… linker, 2,2-bis(aminoethoxy)propane (BAP) and Pluronic® P104 using L-lysine diisocyanate ethyl ester (LDI) or 1,6-Diisocyanatohexane (HDI). The gelation temperature of 20% (w/v) MBCP was in the range of 29 to 31 ºC when tested with three different techniques: rheometer, test tube inversion …
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Controlling molecular interactions to define interfacial phenomena and structure
… the competitive interactions between Pluronic P123 and small molecule surfactants, SMS, (sodium dodecylsulfate, SDS or C12SO4Na, dodecyltrimethylammonium bromide, C12TAB and polyoxyethylene (23) lauryl ether, Brij 35) in the presence of alcohols (ethanol, hexanol and decanol). The …
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Topical Nanoparticulate Formulation of Drugs for Ocular Keratitis
… surfactants including polyvinyl alcohol (PVA), pluronic F-108 and chitosan. NP were characterized with respect to particle size, entrapment efficiency, polydispersity, drug loading, surface morphology, zeta potential and crystallinity. In vitro release of HB from NP showed a biphasic release …
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Development of Binary Composite Solid Microparticles for Improved Intranasal Absorption of Low Permeation Drug Molecules
… of binary composite microparticles with Pluronic® triblock copolymers (polyethylene glycol-polypropylene glycol-polyethylene glycol) should allow increased drug transport across nasal mucosal tissue relative to drug alone. Testing the hypothesis necessitated execution of specific aims …
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Pretreatment and enzymatic hydrolysis of lignocellulosic materials
… hydrolysis experiments in TMR.;Both surfactants, Pluronic F68 and Tergitol NP 9, were effective in enhancing the enzymatic hydrolysis of all the substrate investigated in our TMR system. This is proven by the increased steady state substrate conversion, when either surfactant is added. The …
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Synthesis and Characterization of Thermally Responsive Nanocapsules Surface Decorated With Folic Acid For Targeted Drug Delivery and Cancer Destruction
… we have synthesized and characterized Pluronic F127-chitosan nanocapsules for encapsulation and temperature controlled release of small molecules which could be useful for combining with cryotherapy to achieve improved cancer treatment. To further use these nanoparticles for targeted …
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The synthesis, characterization and catalytic applications of mesocellular silica foams
… (MCF) by using triblock copolymer (PEO-PPO-PEO, Pluronic) micelles to template the formation of silica from tetraethoxysilane precursors. The combination of the polymer amphiphile with a hydrophobic swelling agent (such as trimethylbenzene) resulted in larger pore sizes and more open pore …
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Mechanistic approaches towards understanding particle formation in biopharmaceutical formations. The role of sufactant type and level on protein conformational stability, as assessed by calorimetry, and on protein size stability as assessed by dynamic light scattering, micro flow imaging and HIAC
… the presence of Tween 20, Tween 80, Brij 35 and Pluronic F-68 surfactants led to an increase in the populations of larger particles for BSA samples, whereas IgG2 systems did not notably aggregate under storage conditions MFI was shown to be more sensitive than HIAC technique for measuring …
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Determining soft segment structure-property effects in the enhancement of segmented polyurethane performance
… soft segment domains. Non-crystalline Pluronic copolymer systems had good mechanical properties that resulted from both a strong hard segment incompatibility and a highly mobile soft segment matrix. Hydrogen-bonded hard domain shearing during in-situ tensile deformation yields oriented …
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Direct ink writing of microvascular networks
… fugitive ink consists of a 23 w/w% PEO-PPO-PEO (Pluronic F127) solution, while matrix (25 w/w%) and fluid filler (20 w/w%) are composed of an acrylate-modified form of the Pluronic F127 that can be subsequently photopolymerized. The ink and matrix concentrations exceed the critical micelle …
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