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Showing 1 to 12 of 12 for “"Platelet activating factor (PAF)"”.
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Identification of platelet activating factor (PAF) receptor in equine spermatozoa and its role in motility, capacitation and the acrosome reaction
Platelet activating factor (PAF) is a unique signaling phospholipid that has many biologic properties in addition to platelet activation. PAF roles in reproduction involve ovulation, fertilization, embryo development, implantation and parturition. It may also serve as a biomarker for normal sperm …
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ΛΙΠΟΣΩΜΑΤΑ ΩΣ ΦΟΡΕΙΣ ΤΟΥ ΠΑΡΑΓΟΝΤΑ ΕΝΕΡΓΟΠΟΙΗΣΗΣ ΤΩΝ ΑΙΜΟΠΕΤΑΛΙΩΝ. ΦΥΣΙΚΟΧΗΜΙΚΕΣ ΙΔΙΟΤΗΤΕΣ ΚΑΙ ΔΡΑΣΗ
THE EFFECT OF THE INCORPORATION OF PLATELET, ACTIVATING FACTOR, PAF, IN SMALL UNILAMELLAR RESIDES, SUR, PC AND PC:CHOL, 2:1 AT MOLE RATIOS 1-10%, WAS STUDIED,AS CONCERNING RESICLE SIZE AND STABILITY DURING AGEING OF LIPOSOMAL POPULATIONS FOR TWO WEEKS AT 4 C AND 25 C. THE INTERACTION OF PROTEIN …
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Regulation of Platelet-Activating Factor Acetylhydrolase by Oxidized Phospholipids and Proinflammatory Cytokines
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a monocyte-derived phospholipase A2 that catalyzes the hydrolysis of platelet-activating factor (PAF) and has been implicated in atherosclerosis. Although PAF and other proinflammatory stimuli are postulated to induce the enzyme, mechanisms …
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The central role of the neutrophil in ischaemic/reperfusion injury
… Neutrophil migration in response to factors secreted by the treated endothelial cells was then assessed. The genesis of an inappropriate oxidative burst by the neutrophil upon exposure to endothelial chemoattractants and adhesion molecules was also measured. Finally to appraise how …
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1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine (Platelet Activating Factor): Interactions with Sheep Platelets
<p>Platelet Activating Factor (PAF) seems to link platelet function with allergy and inflammation. Early events associated with the action of PAF on platelets are poorly understood, but PAF appears to interact with a platelet membrane receptor. Two photoaffinity-labelling analogs of PAF, …
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Phosphorylation of TASK-1 and its role in atrial arrhythmias
… to arrhythmogenicity is the phospholipid platelet-activating factor (PAF). PAF acts via a G-protein coupled receptor, present in myocytes, to activate downstream signaling cascades. Data from our lab indicates that inhibition of the two-pore domain potassium channel TASK-1 may contribute …
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An investigation into the direct and indirect effects induced by platelet-activating factor receptor activation in rat isolated lung tissue.
This study looked at the effects of platelet-activating factor (PAF) on rat isolated lung strips and tracheal spirals. Previous studies have shown that PAF induces hyperresponsiveness to the contractile effects of acetyicholine (ACh) and 5- hydroxytryptamine (5-HT) in rat isolated tracheal spirals. …
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The role of oxygen free radicals in the endotoxic shock induced myocardial dysfunction and cellular injury
… (interleukin-1 (IL-1) and tumour necrosis factor (TNF)), platelet activating factor (PAF), activated complement (C3a, C5a) and norepinephrine in the blood. Activated complement, IL-1, TNF and PAF are known to activate polymorphonuclear leukocytes (PMNLs), which on activation lead to …
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Monocyte Modulation of Disease Pathogenesis and Progression in Localized Aggressive Periodontitis
… IgG2 production. In addition, levels of Platelet Activating Factor (PAF) have shown to be elevated in the gingival tissue and gingival crevicular fluid of subjects with periodontitis. The aim of this study was to further characterize the unique phenotype of the myeloid cell by …
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MEDIATORS OF ACUTE INFLAMMATION AND THEIR ROLES IN MODULATING IN VI3^ LEUKOCYTE INFILTRATION AND PATHOBIOLOGIC ACTIVITY IN THE CONJUNCTIVA
… tissues. The prostaglandins (PGs) and platelet-activating factor (PAF) tailed to elicit pronounced conjunctival leukocyte infiltration, and leukocytes did not respond to any of the forms of the eosinophil chemotactic factor of anaphylaxis (ECF-A) or bradykinin (BK). Histamine elicited a …
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Multi-omic Studies of Neutrophils Reveal Programmed Deactivation Phenotypes After Inflammatory Stimulus
… another human pathogen Escherichia coli and platelet activating factor(PAF)/f-met-leu-phi(fMLP). Flow cytometry results demonstrated a significant reduction in neutrophil capabilities to ingest and acidify a second particulate stimulus, with two hours of initial stimulation being the critical …
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Η TETRAHYMENA PYRIFORMIS ΣΑΝ ΒΙΟΧΗΜΙΚΟ ΣΥΣΤΗΜΑ ΜΕΛΕΤΗΣ ΤΩΝ ΔΡΑΣΕΩΝ ΚΑΙ ΤΗΣ ΠΑΡΑΓΩΓΗΣ ΤΟΥ ΠΑΡΑΓΟΝΤΑ ΕΝΕΡΓΟΠΟΙΗΣΗΣ ΑΙΜΟΠΕΤΑΛΙΩΝ
… PHOSPHORYLALCALINE (AGEPC,PAF) BY TETRAHYMENA PYRIFORMIS WAS INVESTIGATED. TIME COURSE EXPERIMENTS INDICATED THAT MAXIMAL UPTAKE OCCURS AFTER APPROX. 2-8 MIN OF INCUBATION. THERE AFTER, THE AMOUNT OF RADIOACTIVITY RETAINED BY THE CELLS IS DECREASING WITH TIME. THE EFFECT OF …