Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Plasmodium chabaudi"”.
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REGULATION OF ADAPTIVE IMMUNE RESPONSES TO PLASMODIUM CHABAUDI MALARIA INFECTION
… CD4 T cell responses using the murine parasite Plasmodium chabaudi, which models chronic human malaria immunology and pathology. First, we show that the CD4 T cell response against malaria consists mostly of a newly described Th1-like Tfh hybrid population. We demonstrated that these cells …
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Hyperinflammatory Experimental Cerebral Malaria: Coagulation and Glial Cell Activation in Plasmodium chabaudi Infection of IL-10-deficient Mice
… is one of the most severe complications of Plasmodium falciparum infection and occurs mostly in young African children. This syndrome results from a combination of high levels of parasitemia and inflammation. While mutations in inflammatory cytokine genes and the levels of cytokines found in …
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A Rapid Concentration and Identification Technique for Human Malaria Infections Using a Mouse Model
… of Balb/c female mice infected with either <em>Plasmodium chabaudi</em> or <em>Plasmodium berghei</em> were drawn into a standard (75x1.2) heparinized capillary micro-hematocrit tube. The tube was sealed at the bottom and centrifuged for 5 minutes at 7,000 revolutions per minute in a hematocrit …
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A study of the immune response in murine experimental malaria, with special reference to the effects of South African medicinal plants, artesunate and chloroquine
… TNF-a/fr1- double deficient) were infected with Plasmodium berghei ANKA {PbA). PbA induced fatal cerebral malaria in wild type mice, which died within 5 to 8 days. In contrast, IFN-f1- and TNF-a/[r1-were completely resistant to PbA-induced cerebral malaria. Both wild type and mutant mice …
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The impact of malaria on the immunogenicity and efficacy of mycobacterium bovis BCG vaccination against mycobacterium tuberculosis in mice
… used a murine model to investigate the effect of Plasmodium species virulence and the timing of infection on BCG-induced immune responses and efficacy against M. tuberculosis both in vivo by aerosol challenge and ex vivo by Mycobacterial Growth Inhibition Assay (MGIA). Methods and Results To …
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Characterisation of the anti-inflammatory potential of ES-62 in autoimmune disease
… the NOD mouse model of Type 1 Diabetes, the Plasmodium chabaudi model of malaria and the Toxoplasma gondii model of toxoplasma, all of which have been linked with Th1-like pathology. However, given the recent reassessment of CIA as a Th17-, rather than Th1-, mediated disease, it has been …