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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 849 for “"Plasma membrane"”.
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Plasma membrane-derived vesicles: composition and function
Plasma membrane-derived vesicles (PMVs) are small, intact, membrane vesicles, which are released by most cells upon activation with various extracellular stimuli. This study identified that procedures used in the isolation of PMVs could be further improved by first sonicating (sonicating …
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Functional Asymmetry of The Immune Cell Plasma Membrane
… between the two leaflets of the bilayer of the plasma membrane. This compositional asymmetry is most prominent for phosphatidylserine (PS), a negatively charged lipid that is found almost exclusively on the cytoplasmic (inner) leaflet of the plasma membrane. This energetically unfavorable …
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Structural studies on the plant plasma membrane calcium-ATPase
The plasma membrane Ca$\sp{2+}$-ATPase is a ubiquitous membrane protein that mediates the active transport of calcium out of the cytoplasm into the cell exterior. In plant cells it is believed to play a major regulatory role in signal transduction by helping to maintain a large gradient of calcium …
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Mechanism of E-cadherin dimerization at the plasma membrane
Embargo set by: Seth Robbins for item 118623 Lift date: 2023-09-17T04:04:53Z Reason: Author requested closed access (OA after 2yrs) in Vireo ETD system
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Regulation of Ras signaling and oncogenesis by plasma membrane microdomains
In this study, we assessed the contributions of plasma membrane (PM) microdomain targeting to the functions of H-Ras and R-Ras. These paralogues have identical effector-binding regions, but variant C-terminal targeting domains (tDs) which are responsible for lateral microdomain distribution: …
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PLASMA MEMBRANE ASSOCIATED GLYCOHYDROLASES: KINETICS PARAMETER CHARACTERIZATION AND BIOLOGICAL FUNCTION
Plasma membrane (PM) sphingolipid pattern and content are the result of a complex network of metabolic pathways, including those potentially involving the activity of PM sphingolipid hydrolases and sphingolipid synthases (1, 2). In human fibroblasts it has been observed a crosstalk between the …
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Targeting Plasma Membrane Phosphatidylserine Content to Inhibit Oncogenic Kras Function
… in human cancers, must be localized to the plasma membrane (PM) for biological activity. We recently showed that the KRAS C-terminal membrane anchor exhibits exquisite lipid-binding specificity for select species of phosphatidylserine (PtdSer). We therefore investigated whether reducing PM …
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Composition and Dynamics of the Plasma Membrane of Entamoeba Histolytica
<p>The study of the parasitic protozoa presents a multifaceted opportunity for biological research. These organisms are eucaryotic cells with many of the biological systems described in higher eucaryotic cells. However, they are adapted to highly specialized environments, invoking sometimes subtle …
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Nuclear and Plasma Membrane Properties of Macrophage Heterokaryons and Hybrids
… cells which proliferates rapidly in vitro. The plasma membrane of the macrophage has specific receptors which enable the cell to ingest antibody-coated sheep red cells and is also rich in a divalent cation dependent adenosine triphosphatase (ATPase) activity. The melanoma cell lacks these …
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Structural Basis for Dishevelled-2 Association to the Plasma Membrane
… of Dishevelled (Dvl), plays a role in cytoplasm-membrane association, which branches the canonical and non-canonical Wnt signaling pathway within the cell. It has been suggested that the DEP domain requires the recruitment of ionic lipids, such as phosphatidic acid, to regulate its localization …
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Physical properties of the plasma membrane studied by local probe techniques
… entwickelt, um die Struktur und Dynamik der Plasmamembran lebender Säugetierzellen zu untersuchen. Dabei lag der Schwerpunkt zum einem auf der mechanischen Kopplung der Membranlipidschicht zu dem darunter liegenden, unterstützend wirkenden Zytoskelett, und zum anderen auf der Beweglichkeit …
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Characterization of sodium transport at the plasma membrane of Spergularia marina
… entails either passive exclusion mediated by low plasma membrane permeability or active exclusion of passively acquired Na$\sp{+}$ which has moved down its electrochemical gradient into the cell. Whole plant studies using the halophyte Spergularia marina have demonstrated high permeability for …
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Linking Architecture and Function of Endoplasmic Reticulum - Plasma Membrane Contact Sites
… of eukaryotic cells form an intricate network of membrane contact sites (MCS) and thereby promote cellular functions such as lipid metabolism, signalling and organelle biogenesis. The formation of cortical endoplasmic reticulum (cER) - plasma membrane (PM) contacts in budding yeast cells is …
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Plasma membrane calcium ATPase 4 (PMCA4) and inflammation of the aortic endothelium
… vascular diseases, including atherosclerosis. Plasma Membrane Calcium ATPase 4 (PMCA4) belongs to a family of transmembrane ion transporters that extrude calcium from the cytosol to the extracellular environment (Strehler, 2015). They are the only high-affinity Ca2+ extrusion system in …
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Role of plasma membrane ATPase4 in the pathophysiology of pulmonary arterial hypertension
… suggesting that calcium transporters like Plasma Membrane Calcium ATPase 4 (PMCA4) may play an important regulatory role. PMCA4, encoded by ATP2B4, maintains calcium homeostasis and modulates signalling pathways through its scaffolding function at the plasma membrane. This study …
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Lipid Composition and Configuration Drive Biophysical Properties of The Mammalian Plasma Membrane
… us to consider the existence of an elusive membrane resident with opposing asymmetry. Cholesterol, the most abundant PM lipid, has wildly conflicting reports of PM distribution, likely due to its unique structure that allows for rapid interleaflet flipping. We hypothesize that the PM …
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The Interaction of 1-Anilino-8-Naphthalenesulfonate With The Thyroid Plasma Membrane
Made available in DSpace on 2014-12-14T05:40:41Z (GMT). No. of bitstreams: 1 7708985.pdf: 11596018 bytes, checksum: d1d05f152f5f84ed7de7b388aadec631 (MD5) Previous issue date: 1976
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Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain
… or internal cues. Often, local changes to plasma membrane (PM) topography are involved in mediating cell shape change. The centrosome is an organelle that can organize cortical domains and affect PM topography by locally pulling the PM inward. Is the role of the centrosome in organizing …
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