Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"Plant Immunity"”.
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Molecular recognition in plant immunity
Plant pathogens constitute a major threat to global food security. The use of naturally resistant crop varieties can limit crop losses, however new races of pathogen can arise that are able to overcome these defences. Plant breeding for race-specific resistance typically relies on …
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An investigation into the role of ubiquitination in plant immunity
Plants have developed elaborate defence mechanisms to protect themselves against pathogens. Recently, the ubiquitin-proteasome pathway has been proven to play important roles in regulating plant disease resistance. Previously, the tobacco (Nicotiana tabacum) ACRE276 and its Arabidopsis homolog …
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Dissecting the role of plant immunity in plant-aphid interactions
… phloem-feeding insects that cause loss in plant productivity worldwide. This occurs through the removal of photoassimilates and the vectoring of hundreds of plant viruses. Plants possess a complex immune system in order to defend themselves from a range of pathogens including bacteria and …
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Investigating the regulation of plant immunity by the N-degron pathway
Crop losses arising from plant diseases present a major obstacle for efforts to meet the food demands of a growing global population, and these impacts may be exacerbated by unprecedented rates of climate change. The Ubiquitin Proteasome System (UPS) contributes to the regulation of plant immunity …
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Large-scale studies and biophysical analysis of systems involved in plant immunity.
The field of plant immunity has progressed significantly in the last decade, driven primarily by both forward and reverse genetics and to a lesser extent by molecular biology techniques. However, many unknowns still remain before a more complete picture of this system can be achieved, which hinders …
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Investigation into the function of Pi17316, a novel effector protein from <i>Phytophthora infestans</i> that compromises plant immunity
Plants are fundamental to life on Earth, especially for the role they play in the food chain. With the world human population predicted to exceed 9 billion by 2050 the pressure on our agricultural system is set to increase. Not only does agriculture have to expand in order to feed this ever growing …
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Modeling the dynamics of the plant immune response
… My PhD study focuses on dynamic modeling of plant immunity, a plant defense response induced by pathogens. There are two well-defined modes of inducible immunity of plant to overcome pathogen attack, namely pattern triggered immunity (PTI) and effector triggered immunity (ETI). Researchers …
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Identification of <i>Phytophthora capsici</i> nuclear effector targets to bolster host immune signalling and resistance pathways
Phytophthora capsici is a plant pathogenic oomycete that causes huge damage to agriculture worldwide. Its virulence is driven by effectors, which target various host cell components in order to suppress plant immune responses. To enhance plant immunity and to generate new resistances in crops, it …
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STRUCTURE-FUNCTION STUDIES OF TRANSLOCATED EFFECTORS FROM THE LATE BLIGHT PATHOGEN
… However, in response to this manipulation, plants have evolved to monitor for effectors and trigger defence responses. Amongst plant pathogens, oomycetes of the genus Phytophthora have arguably caused almost unrivalled levels of human suffering and represent significant threats to global …
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Structural Investigation of Bacterial Pathogenesis and Host Immune Response
… a variety of diseases in human, animals, and plants. Ongoing research is focused on revealing how several essential proteins manipulate the host immunity to cause disease. It’s necessary to understand the host-bacterial interactions as it is also a potential strategic hotspot for developing …
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Regulation of receptor kinase-mediated immune signalling by dynamic phosphorylation
Plants recognize pathogen-associated molecular patterns (PAMPs) via cell surface-localized pattern recognition receptors (PRRs), initiating a broad-spectrum defense response against pathogens, known as PRR-triggered immunity (PTI). However, immunity comes at a cost; and immune responses need to be …
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Characterisation of the AT4G11100 gene, a negative regulator of disease resistance in Arabidopsis thaliana
Plants have evolved a complex system of defence to prevent pathogen establishment. The Arabidopsis thaliana cir1 (constitutively induced resistance 1) mutant displays enhanced resistance to infection by the virulent bacterial pathogen Pseudomonas syringae and constitutively expresses a number of …
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Identification and functional characterization of RXLR effector proteins that are conserved between downy mildew pathogens and Phytophthora species
Diverse pathogens secrete effector proteins into plant cells to manipulate host cellular processes. The genome of Hyaloperonospora arabidopsidis (Hpa), the causative agent of downy mildew of Arabidopsis, contains at least 134 candidate RXLR effector genes. These genes contain an RXLR motif required …
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DISCOVERY AND FUNCTIONAL ANALYSES OF HESSIAN FLY EFFECTOR-ENCODING GENES
… of gene-for-gene interac- tion between host plants and parasitic insects. The Hessian fly uses secreted effector proteins to control susceptible host plant physiology, transforming the plant cells in a nutritive tissue to support the developing insect larva. HF-resistant wheat cultivars …
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Unveiling and exploiting <i>Phytophthora capsici</i> effectors and their host targets, with an emphasis on CRN effector proteins
Phytophthora capsici is a devastating plant pathogen for which virulence is aided by the secretion of effectors, including cytoplasmic effectors from the CRN (CRinkling and Necrosis) family.<br/><br/>CRN effectors were first described in oomycetes by their capacity to induce host cell death. …
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Investigation of the molecular basis of PAMP-induced resistance
… receptors (PRRs) constitutes the first layer of plant innate immunity. Although details of early immune signaling events are starting to be unveiled, the molecular mechanisms leading to restriction of pathogen growth are still poorly understood. To gain more insight into this process, two …
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Small RNAs in Tomato: from defence to development
… is a major regulator of gene expression in plants, controlling from development to transposable element silencing and stress responses. As part of the silencing machinery, micro (mi)RNAs orchestrate silencing of their targets, either directly or through cascades of secondary small …
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Understanding the role of host amino acid transporters in nutrient acquisition by oomycete pathogens
… that extract nutrients exclusively from living plant cells. As a part of its obligate biotrophy lifestyle, Hpa has lost the ability to assimilate inorganic nitrogen and sulfur. It thus has to acquire these nutrients from the host in an organic form; possibly amino acids. Using a reverse genetic …
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The Impact of Iron Deficiency on Plant-Oomycete Interactions
Plants are sessile organisms adapted to cope with dynamic changes in their environment. Abiotic stresses, such as heat, drought, or nutrient deficiency must be overcome simultaneously with biotic threats such as pathogens and herbivores. Oomycete pathogens represent a significant threat to global …
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Histone Variant H2A.Z Substitution Mediated by the SWR1-like Complex is a Novel Transcriptional Regulatory Mechanism Controlling Defense Genes and Immunity in Plants
Plants have evolved a complex immune system as a result of an evolutionary arms race between the host and various pathogens. One of the most vigorous immune responses in plants involves resistance (R) proteins, which detect the presence of effector molecules from pathogens and trigger a large-scale …
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