Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Plakoglobin"”.
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Elucidating the Role of Plakoglobin in Embryonic Stem Cell Culture
… the naïve pluripotency network and upregulated Plakoglobin. A cell-adhesion protein located in both adherens junctions and desmosomes. It is important for tight cell-cell adhesions and known for its function in tissues undergoing high mechanical stress. Plakoglobin also occurs in the cytosol, …
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Dissecting Pluripotency and Mammalian Embryonic Development via Droplet Microfluidics
… of the pluripotency network. I then identified plakoglobin, a homologue of b-catenin, as one of the strongest upregulated proteins upon microgel encapsulation. However, molecular functions of plakoglobin in embryonic stem cells remain largely elusive. To investigate plakoglobin’s potential role …
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A NOVEL DROPLET-BASED PLATFORM FOR TUMOR SINGLE-CELL ENCAPSULATION AND METASTATIC MULTICELLULAR CLUSTER MODELLING
… of adhesion and survival markers such as plakoglobin and BCL-2. This approach provides a robust tool for advancing mechanistic understanding of metastasis with high-throughput and precise environmental control. This bridges the fields of engineering microfabrication and cancer …
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Regulation of apoptosis and desmosomes by RhoE
… adhesion and a component of demosomes – plakoglobin – was shown to play a key role in RhoE-mediated resistance to apoptosis.
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Molecular genetics of arrhythmogenic right ventricular and dilated cardiomyopathy in South Africans
… plakophilin 2, desmocollin 2, desmoglein 2, and plakoglobin), (2) establish the presence of a founder effect in families with a recurrent mutation in the plakophilin 2 (PKP2) gene, (3) investigate whether single nucleotide polymorphisms found in desmosomal genes affect gene expression, and (4) …
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The Sodium Pump Regulates Sperm and Sertoli Cell Function
… ATP1A4 interacted and co-localised with plakoglobin (member of β-catenin family of proteins involved in cell adhesion) in the equatorial segment of capacitated sperm; this suggests a potential role for these proteins in sperm-oolemma fusion. During investigation of ATP1A4 involvement in …
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Zell- und molekularbiologische Charakterisierung neuartiger Zell-Zell-Verbindungsarten in Glioma-Zellen und mesenchymalen Stammzellen
… weiteren armadillo-Proteinen p120ctn, ARVCF und Plakoglobin sowie - überraschenderweise - dem von Desmosomen her bekannten Protein Plakophilin 2 und den - von "Tight Junctions" bekannten - Plaque-Proteinen ZO-1, ZO-2 und Cingulin komplexiert sind und zusammen mit Afadin und dem Actin-bindenden …