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Showing 1 to 1 of 1 for “"Pimecrolimus"”.
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CHEMOENZYMATIC APPROACHES TO THE PREPARATION OF BIOLOGICALLY ACTIVE COMPOUNDS
… is required to transform ascomycin into pimecrolimus, its 32-epi chlorine analogue, an immunomodulator useful for the treatment of inflammatory skin diseases. The advantage offered by enzymes, showed to be not only their ability to regioselective discriminate between the two secondary …