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Showing 1 to 1 of 1 for “"Pim kinases"”.
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Pim Kinase Inhibition: Single Agent and Combination Approaches In B-Cell Lymphoma
… site for Moloney murine leukemia virus (Pim) kinases are Ser/Thr/Tyr kinases. They modulate B-cell development but become oncoproteins and promote cancer development once overexpressed. Containing three isoforms, Pim-1, -2 and -3 are known to phosphorylate various substrates that regulate …