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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"Phytoestrogens."”.
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Quantitative analysis and metabonomic study of phytoestrogens in Africans
Phytoestrogens have been widely studied in various parts of the world. However, little is known about the availability, absorption, metabolism and its biochemical effects in Africans. The principal aim of this research was to investigate the phytoestrogen content in six African staple foods, their …
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Effects of exercise and phytoestrogens on white adipose tissue health in estrogen deficient rodents
… wheel running (Chapter 3) or a diet rich in phytoestrogens (SOY) (Chapter 4) can improve WAT health following OVX in rodents. Female OVX rats selectively bred for high (HCR) or low (LCR) intrinsic aerobic capacity were fed a high fat diet (HFD; 45%) to induce obesity and had access to a …
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Analyse molekularer Mechanismen der ERα- und ERβ-vermittelten Wirkung spezifischer Liganden und des Phytoestrogens Genistein
… Wirkungsweisen gewebespezifische Einflüsse des Phytoestrogens Genistein (Gen) näher charakterisiert werden. Es konnte gezeigt werden, dass nach einer subkutanen Applikation der knochenprotektive Einfluss von Gen mit dem von Estradiol (E2) vergleichbar ist, durch die Kombination mit Bewegung …
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Effect of phytoestrogens on breast and prostate cancer cell lines – potential implications for bone metastasis
The effect of phytoestrogens on breast and prostate cancer cell lines – potential implications for bone preferential metastasis to bone Safaa Salman Mezban AL-Thamiree Abstract Many epidemiological studies indicate that diets rich in phytoestrogens (PE), especially soy and grain products, may be …
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Estrogenic and androgenic endocrine disrupting activity and risk assessment of phytoestrogens in Kenyan soya-based weaning flours
The presence of phytoestrogens (PEs) in soya based baby foods has attracted a lot of attention due to their ability to act as endocrine disruptive compounds (EDCs). Infants and young children have critical windows of sensitivity to EDCs during their development. Positive health effect of PEs are …
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Isolation and characterisation of anti-diabetic pharmacological activities of phytoestrogens and components of Moringa peregrina (Forssk) Fiori
… no large changes in expression. Dietary phytoestrogens have been shown to play a beneficial role in obesity and diabetes, so the second part of this study investigated the effect of phytoestrogens on glucose uptake. Three phytoestrogens (daidzein, formonontein and genestin, which are …
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Breast Cancer Progression and Phytoestrogen Interactions with Estrogen Receptors
… studies suggests that dietary consumption of phytoestrogens may modulate disease progression. This study hypothesises that the interaction between some phytoestrogens (present in the pre-diagnosis diet or in the new diet adopted by breast cancer patients) and specific ER isoforms displayed in …
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Factors Influencing Early Embryonic Development in the Pig
… from the phytoestrogen study indicate that the phytoestrogens, daidzein and genistein at concentrations (0, 10 nM, 30 nM, 100 nM, 300 nM, 1 muM and 3 muM) had no developmental effect on pig embryos, however pig embryos cultured with 3 muM daidzein may improve blastocyst formation over control …
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A Novel Phytoestrogen that Acts as an Agonist for Human Estrogen Receptors.
… However, certain plant-derived compounds or phytoestrogens have been identified that mimic estrogens and act as agonists and/or antagonists of ERs, depending on subtype and target tissue. Understanding how phytoestrogens interact with ERs, and therefore effect the estrogenic response, may …
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Activation of proestrogens from hops by human intestinal bacteria: conversion of isoxanthohumol into the potent phytoestrogen 8-prenylnaringenin
… in biological activity was also noted for other phytoestrogens and related with variable intestinal bacterial metabolism, the goal of this work was to investigate whether intestinal bacteria also determine the final activity of hop phytoestrogens by combining batch incubations with SHIME, rat and …
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Type II Estrogen Binding-Site Agonist: The Synthesis and Biological Evaluation of the Enantiomers of Methyl-Para-Hydroxyphenyllactate (MeHPLA)
… relationship to a group of compounds called "phytoestrogens" which, along with MeHPLA, have been observed to suppress the cellular proliferation of estrogen sensitive MCF-7 breast cancer cells in vitro. Additionally, MeHPLA has been observed to suppress the growth of rat uteri in vivo. The …
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Efeito do relaxamento induzido por diosgenina em artéria mesentérica de rato após administração de 17-β estradiol.
… researchers have attempted, in studies with phytoestrogens, an alternative to impro ve the treatment of this illness, since hormone replacement therapy harms to patients with breast or uterine cancer. Among various existing phytoestrogens tried to assess the cardiovascular activity of …
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THE EFFECTS OF ESTROGENIC COMPOUNDS ON ADIPOGENESIS VIA PPARγ AND CANONICAL WNT SIGNALING
… homeostasis in obese rodents. Alternatively, phytoestrogens, such as genistein and daidzein were reported to induce adipocyte differentiation through potential interactions with PPARγs, canonical WNT proteins, and estrogen receptors (ER) signaling. The current investigation was conducted to …
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Isotopic labeling of isoflavones from plant cell and organ culture for metabolic tracking in animal models
Kudzu and red clover isoflavones are phytoestrogens that have been investigated as alternatives to estrogen replacement for treatment of osteoporosis, cardiovascular disease, and neurological disorders. However, the pharmacokinetics of these compounds are not clearly understood. In the present …
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Organ and primary culture of medaka (Oryzias latipes) testis: Test systems for the analysis of cell proliferation and differentiation
… inhibitory effect. To investigate the effect of phytoestrogens on cell proliferation in spermatogenesis, selected flavonoids [genistein (1, 10, 100 µg/ml), quercetin (0.01, 1, 100 µM), and 8-prenylnarigenin (0.001, 0.1, 1, 10 µM)] were added to medaka testis primary cultures. Genistein and …
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Der Einfluss von Phytoöstrogenen, mehrfach ungesättigten Fettsäuren, Vitamin D und K auf den Knochenstoffwechsel und die Mikroarchitektur des Knochens
… research on alternatives is of current interest. Phytoestrogens, polyunsaturated fatty acids, as well as vitamins D and K were found to have a positive impact on bone in vitro and partially in vivo. In the present study effects of a combination of genistein, polyunsaturated fatty acids and vitamin …
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Evaluation of a modified food frequency questionnaire to measure lignans in Australian men and women
Phytoestrogens are plant compounds that possess estrogenic and biological properties that have been postulated to protect against chronic diseases. Isoflavonoids and lignans are two main classes of phytoestrogen that have been investigated for their estrogenic efficacy and occurrence in the human …
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Investigations into the role of exogenous estrogenic endocrine disrupting chemicals on immune dysregulation in autoimmune disease
… severity. Mice fed a diet devoid of exogenous phytoestrogens developed significantly reduced glomerulonephritis and glomerular immune complex deposition compared to mice fed a diet containing soy isoflavones. Diet also influenced cytokine production and epigenetics of LPS-stimulated splenic …
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The direct effects of estradiol and several xenoestrogens on cell numbers of early- vs. late-stage prostate cancer cells
… consumption of safe dietary concentrations of phytoestrogens and acceptable exposure levels to BPA.
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Cellular Mechanisms of Resveratrol's Interaction with Mitochondrial Reactive Oxygen Species Metabolism
… structurally similar to resveratrol and seven phytoestrogens predicted to bind to estrogen receptor beta were screened for their effects on MnSOD, proliferative growth rates and stress resistance in cultured mammalian cells. Several of these compounds were able to mimic the effects of …
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