Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Phytocannabinoids"”.
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Characterizing the Developmental and Reproductive Toxicities of Cannabidiol and Δ9-Tetrahydrocannabinol
… of the two most prevalent and widely used phytocannabinoids. While most patients with drug-resistant forms of epilepsy and debilitating seizures choose cannabinoids in desperation, more research is necessary into their developmental toxicity to better understand both their therapeutic and …
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From macromolecular crowding to transcriptional regulation: Exploring the complexities of cytochrome P450s, cannabinoids, and inflammation
… has opened the door to comparisons with phytocannabinoids and questions about how the presence This work is aimed at untangling the complex web of P450 interactions with the environment and cannabinoids, the regulation of inflammation, and the intersection of these two topics. Described …
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Examination of Brain-Fatty Acid Binding Protein Interaction with Hydrophobic Ligands and Micelles
… such as fatty acids, endocannabinoids, and phytocannabinoids. Transport of these ligands is mediated through both protein-membrane and protein-protein interactions. FABP7 bears a nuclear localization signal that allows ligand-dependent transport to the nucleus through the nuclear pore …
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Enzymology of lipid metabolism by CYP2J2 as controlled by multiple-ligand binding events
… with cannabinoids derived from marijuana (phytocannabinoids), including appetite, mood, and inflammation. Endocannabinoids are also substrates of CYP2J2, and the epoxide metabolites of these endocannabinoids have been shown to be anti-inflammatory. In Chapter 4, we determine that …
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Medicinal Chemistry of Cannabis and Cannabinoids
… cannabinoid receptor activities of individual phytocannabinoids with reasonable accuracy and revealing differences in cannabinoid receptor responses between pure cannabinoids and cannabis extracts. Finally, the total synthesis and characterization of two pharmaceutically novel cis stereoisomers …
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Genetic Variation and Sex Mediate Differential Responses to ∆-9-tetrahydrocannabinol among Inbred Mice
… hundreds when Cannabis components known as phytocannabinoids were characterized and later isolated. In the 1970’s, ∆9-tetrahydrocannabinol (THC) was isolated and recognized as the major constituent responsible for the psychoactive and intoxicating effects associated with consumption of …