Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 25 for “"Physiological impact"”.
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Investigating The Single Cell Heterogeneity and Physiological Impact of Mistranslation
… cells have a variety of phenotypes. The physiological heterogeneity observed in populations has been attributed to variations in the processes of gene expression. For example, promoter expression has been shown to be heterogeneous within a population and contribute to increased stress …
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A Novel Cardiac Function of Sumo2/3 and Senp5 Dependent Pathway and Its Physiological Impact On Congestive Cardiomyopathy
… and SENP5 dependent pathway and its physiologic impact on congestive cardiomyopathy</strong></p> <p>Publication No.___________</p> <p>Eun Young Kim, M.S.</p> <p>Supervisory professor: Robert J. Schwartz, Ph.D.</p> <p>SUMOylation regulates diverse cellular processes including transcription, cell …
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Biochemical Characterization of <i>Toxoplasma gondii</i> Type II NADH Dehydrogenases - Physiological Impact on Mitochondrial Functions and Energy Metabolism
… TgNDH2 activity as a target of HDQ, the physiological impact of HDQ activity on mitochondrial functions was examined next. Intracellular parasites exposed to HDQ displayed a significant collapse of the mitochondrial membrane potential (∆Ψm). Strikingly, ∆Ψm in living parasites was …
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Examining Hessian fly (Mayetiola destructor) management concepts and quantifying the physiological impact of hessian fly feeding on post-vernalization selected cultivars of winter wheat in Kansas
… mature wheat (Feekes 7-10), post-vernalization, impact plants, aside from lodging. Greenhouse and field infestations of a susceptible cultivar, Fuller, showed that significant losses of culm height (cm), number of seeds/spikelet, and seed weight will result from as few as 1 larva /culm. Yield …
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THE EFFECTS OF ORAL ARGININE ON ITS METABOLIC PATHWAYS IN SPRAGUE-DAWLEY RATS
… role. However, there is a lack of clarity on the physiological impact of oral arginine on its metabolic pathways in the human body. As a versatile molecule, arginine is metabolized by multiple enzymes including arginase, nitric oxide synthase, arginine decarboxylase, and arginine:glycine …
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Mitochondrial Haplotype Influences the Impact of Simulated Climate Warming on a Tropical Ectotherm
… a warm environment therefore has a much larger physiological impact than does a comparable temperature increase in a cool environment. In studies recently conducted by my faculty mentors and their students on the Neotropical pseudoscorpion, Cordylochernes scorpioides (Zeh et al. 2012, 2014), it …
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Photoplethysmorgraph-derived respiration
… to provide an objective evaluation of the physiological and neurocognitive impact of human electromuscular muscular interference (HEMI) devices in humans. The initial step is to understand their physiological impact, which is characterized by vital signs. Volunteers are recruited from HEMI …
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Exploring their dark side or death before DNF: Ultra-athletes motivation to compete in and complete ultra-distance races
… There is an expanding body of research into the physiological impact of such undertakings on the human body. Long-distance racing impacts adversely on the body of the athlete. Research has included the nutritional needs and calorie deficit in ultra-racing; difficulties in maintaining euhydration …
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Regulation of estrogen receptor-alpha mediated gene expression and endocrine resistance through estrogen receptor-alpha phosphorylation and micro-RNA in breast cancer
… 106, 118, 167, 236, and 305, and examined their impact on receptor half-life, the agonist and antagonist balance of selective estrogen receptor modulators (SERMs) and selective estrogen receptor downregulators (SERDs), the regulation of ER transcriptional activity, and stimulation of cell …
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Characterization of the impacts of the physiological response of vegetation to increasing levels of atmospheric carbon dioxide
… simulations have been conducted to examine the impact of the physiological response of vegetation to varying levels of CO2 near the leaf surface. Results showed that the impact of increased CO2 on stomatal conductance generally led to statistically significant changes in latent heat flux (LHF), …
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Physiological role and quantitative aspects of human Nonsense-mediated mRNA decay (NMD)
… of the role and mechanism of this pathway, the physiological impact of NMD on humans is not yet fully uncovered. To explore the functions of NMD in humans, I combined RNAi against the essential NMD factor UPF1 with genome-wide microarray analysis. My research indicate that NMD affects the …
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Causal Inference and Evidence-Grounded Language Models for Trustworthy Personalized Clinical Decision Support
… intraoperative events and their downstream physiological impact, supporting personalized surgical decision-making. Second, we establish evidence-grounded reasoning as a critical bridge between personalized predictions and actionable recommendations. We introduce Evidence-Guided Diagnostic …
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Effects of deficit irrigation frequency on plant growth, water use and physiology of Pelargonium x hortorum and tomato (Solanum lycopersicum L. cv. Ailsa Craig)
… quality. However, our understanding of the physiological impact of this approach in containers in a peat based substrate is limited. Pelargonium x hortorum Bullseye plants were grown in glasshouse conditions under well-watered (WW; daily replacement of 100% of evapotranspiration (ET)), …
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Assessing the risk of ocean acidification for scleractinian corals on the Great Barrier Reef
Ocean acidification will impact the photo-physiology of reef-building corals as it can lead to dysfunction of the symbiosis and loss of productivity. The major objective of this thesis was to provide insight into the mechanism of CO₂₋induced bleaching and productivity loss across multiple …
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Régulation de voies de signalisation par deux acteurs de la voie Nonsense-mediated Decay, Dhx34 et Nbas: la cas particulier de l'adénohypophyse.
… involved in the abundance regulation of several physiological transcripts. For example the NMD is involved in the regulation of the concentration of splicing factors in a process called AS-NMD (Alternative splicing- Nonsense-mediated Decay), establish a threshold for some stress responses such as …
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Investigating The Distinct Role of Pd-L2 In Modulating Human T Cells Responses
… of primary human T cells and elucidated the physiological impact of the differential signaling induced by PD-ligands through PD-1 on T cell function. Taken together, our work provides a more solid immunobiological foundation for clinical translation of PD-L2 and defines its non-redundant role …
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Analisis faktorial dimensi altruisme pada relawan bencana alam
… Malang. So that it affects the material and physiological impact toward the people around. Many people voluntarily sincere provide time and energy to help in time of disaster and they used to call themselves as volunteers who are always ready when needed. Surely helping behavior is driven by …
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Assessing the ecological vulnerability of natural flood defences and risks to agricultural land following seawater flooding
… growing need to understand how these events will impact coastal ecosystems, and the measures that can be taken to mitigate against these effects and protect natural resources. Furthermore, with increased pressures placed on agriculture to meet food demand, protecting arable land resources in …
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Emerging anabolic drugs - investigation of the in vitro and in vivo metabolism of selective androgen receptor modulators
… relevant species and better understand their physiological impact, this thesis studies the in vitro and in vivo metabolism of key SARM compounds. <br/><br/>To evaluate the use of liver homogenates as an in vitro tool to rapidly produce SARM metabolites, cattle liver homogenates, S9 fractions, …
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