Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 163 for “"Photoreceptor"”.
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rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration
The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) …
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Apoptosis in retinal photoreceptor degeneration.
Apoptosis in retinal photoreceptor degeneration.
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cis-Regulation in the Mammalian Rod Photoreceptor
<p>Transcription factors regulate the expression level of target genes by binding to <italic>cis</italic>-regulatory elements (CREs) present in gene promoters. The goal of my thesis research is to define the sequence components of CREs that determine transcriptional output. In order to accomplish …
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Role of oxidative stress in photoreceptor degeneration
… associated with progressive degeneration of photoreceptor cells. Mutations in numerous genes have been implicated in RP, which have distinct pathophysiological mechanisms and lead to retinal degeneration at different rates. The aim of this thesis was to investigate the role of oxidative …
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Steroid induced neuroprotection of damaged photoreceptor cells
… Norgestrel worked. To this aim, the 661W cone photoreceptor-like cell line and ex vivo retinal explanting was utilised. We found that Norgestrel induces a increase in neuroprotective basic fibroblast growth factor (bFGF) with subsequent downstream actions on the inhibition of glycogen synthase …
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Cell Death Mechanisms in Drosophila Differentiated Photoreceptor Neurons
… the Drosophila retina, cell death terminates and photoreceptor neurons complete their differentiation process. We use these terminally differentiated photoreceptor neurons as a system to study neurodegeneration. We first adapt and develop fluorescent tools for photoreceptor visualization in vivo. …
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The role of spectrin in Drosophila photoreceptor development.
… the specific effects of spectrin on Drosophila photoreceptor development. In fruit flies the mosaic technique can be used to express both the mutant and the wild-type tissue in a single eye. The mosaic eyes were dissected, fixed, and mounted onto a slide and analyzed using confocal microscopy. …
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Light deprivation and presumed photoreceptor cells in Hydra littoralis
Typescript (photocopy).
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Functional groups in rhodopsin and the rod photoreceptor membrane
Contains fulltext : mmubn000001_188726705.pdf (Publisher’s version ) (Open Access)
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The Role of Peripherin in Photoreceptor Outer Segment Morphogenesis
… eyes. This task is performed by the rod and cone photoreceptors, which both contain a highly evolved sensory cilium called the outer segment. The outer segment is a specialized cellular compartment that contains all of the protein machinery involved in converting the initial light signal into an …
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Rod Photoreceptor Regeneration in a Zebrafish Model with Retinitis Pigmentosa
… degenerative diseases is progressive loss of photoreceptors until one is completely blind. Unlike mammalian models, Zebrafish have the ability to naturally regenerate their neurons after injury or disease is detected. We have generated a zebrafish model with the most common autosomal dominant …
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Study of the role of miR-204 in photoreceptor development
… in regulating the retina development especially photoreceptors. In particular, I focused on miR-204, one of the miRNAs our laboratory is mostly focusing on, and whose role in multiple aspects of eye development has been elucidated in the past few years from our lab and other groups. I dissected …
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Chromatic sensitivity: effects of light level and selective photoreceptor adaptation
… the excitation levels produced in each class of photoreceptor. The ability to see colours and to notice small colour differences is strongly affected by both the spectral composition and luminance level of the adapting light. Knowledge of the limits of colour detection is important in setting …
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Multi-Scale Structure and Dynamics of Visual Signaling in Drosophila Photoreceptor Cells
A general problem in science today is how to understand complex systems. An emerging and promising approach makes the bold assumption that complex systems adhere to particular design principles. The power of this is that design principles by definition impose an intuitive nature on a system by …
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Deciphering Underlying Mechanisms Of Photoreceptor Outer Segment Degradation; Involvement Of Intracellular Trafficking
… AMD is characterized by the degeneration of photoreceptors and retinal pigment epithelium (RPE) cells in the macula region of the retina. RPE maintain the health of the retina by providing support to the photoreceptor cells and the retina through various tasks. One major task RPE cells are …
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Quantum Mechanical/Molecular Mechanical Studies of F1-ATPase and a Plant Photoreceptor
Submitted by Meng Tao (mengtao2@illinois.edu) on 2012-10-11T20:13:47Z No. of bitstreams: 1 Dittrich.pdf: 21387898 bytes, checksum: 3039bb041b2ef5c8c1f9213547feeea4 (MD5)
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Quantum Mechanical/molecular Mechanical Studies of F(1)-Atpase and a Plant Photoreceptor
The plant blue-light receptors of the phot family mediate plant phototropism and contain two light, oxygen, and voltage (LOV) sensitive domains as photoactive elements. We have performed QM/MM simulations of the photocycle of a complete Phot-LOV1 domain from C. reinhardtii. We have investigated the …
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