Global ETD Search
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Showing 1 to 4 of 4 for “"Photopharmacology"”.
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Customizing Multifunctional Bidirectional Neural Interfaces through Fiber Drawing
… was then leveraged to enable the translation of photopharmacology, a method that attaches optical switches to chemicals or proteins, to in vivo experiments. This approach enabled the reversible optical control of place preference behavior in freely moving mice. Finally, a fiber-based closed-loop …
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Photocontrol of Antibacterial Activity
… photoreleasable protective groups to cage drugs. Photopharmacology is based on bioactive molecules that incorporate in their structure a molecular switch. The photoactive moiety can undergo an isomerization process that induces changes in the molecule properties like dipole moment, geometry, or …
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SYNTHESIS, CHARACTERIZATION AND EVALUATION OF BIOACTIVE MOLECULES LINKED TO PHOTOREMOVABLE PROTECTING GROUPS FOR SPATIO-TEMPORAL CONTROL OF THEIR ACTIVITY THROUGH PHOTOACTIVATION
… the last decade to investigate such processes, photopharmacology has emerged as a powerful tool, as it exploits light to control biological functions. In particular, optopharmacology enables the regulation of pathophysiological processes through the use of molecules that become bioactive upon …
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Azobenzenes for the development of therapeutics
Azobenzenes are photochromic molecules, commonly utilised for their ability to undergo light-mediated isomerisation. This unique property enables them to modulate biological systems upon their incorporation. Chapter 1 explores the utilisation of azobenzenes for peptide stapling, that has gained …