Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Photoacoustic tomography"”.
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Novel contrasts in photoacoustic tomography
<p>Photoacoustic tomography (PAT) combines rich optical contrast and high ultrasonic resolution in optically scattering tissue at depths. Taking advantage of its 100% sensitivity to optical absorption, PAT has been widely applied to structural, functional and molecular imaging, with both endogenous …
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Quantification and Reconstruction in Photoacoustic Tomography
… the method using the optical-resolution photoacoustic microscopy: OR-PAM) and the acoustical-resolution photoacoustic microscopy: AR-PAM) in the optical ballistic regime and in the optical diffusive regime, respectively. The data acquisition speed in photoacoustic computed tomography: …
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Photoacoustic Tomography of Diabetes and Reporter Genes
<p>Photoacoustic Tomography (PAT) is a hybrid technology which combines light absorption contrast with ultrasonic detection to achieve deep imaging of normally obscured absorbing molecules in tissue. PAT's inherent background free, super-depth imaging capability makes it particularly well suited …
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Multi-spectral Deep Tissue Quantitative Photoacoustic Imaging
<p>Photoacoustic tomography (PAT) detects the acoustic signals generated by optical absorption from chromophores. Using oxy- and deoxy-hemoglobin, multi-spectral PAT can image vasculature structure, and provide functional information. Most of the current PAT imaging studies face four challenges: …
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Enabling Biomedical Imaging Diagnostics using Optical Methods
… the second part of the thesis, a novel hybrid photoacoustic and diffuse optical tomography hand-held probe is constructed for improving the accuracy of diffuse optical imaging. The probe design incorporates photoacoustic technology into the standard diffuse optical imaging systems. The …
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Dual-modality thermoacoustic and photoacoustic imaging
… The combined contrasts from thermoacoustic and photoacoustic tomography: TAT and PAT) can potentially predict early stage breast cancer. We have designed and engineered a breast imaging system integrating both thermoacoustic and photoacoustic imaging techniques to achieve dual-contrast: …
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Activatable photoacoustic contrast agents for sensing and delivering nitric oxide, and development of small molecule photoacoustic platforms with improved properties for in vivo imaging
… in cell culture; other methods, including photoacoustic imaging (PAI), ultrasound (US), magnetic resonance imaging (MRI), and positron emission tomography (PET), each provide unique capabilities and can be used effectively at diverse length scales. In the Chan group, we are particularly …
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Indocyanine Green J-aggregate Nanoparticles for Detection of Senescent Cells
… nanoparticle, exhibiting fluorescent and photoacoustic imaging properties for longitudinal *in vivo* bioimaging of senescence. First, in this thesis the synthesis of J-aggregates of indocyanine green was explored with the aim to develop a high contrast photoacoustic probe. Reported methods …
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Advancing Photoacoustic Imaging Technology with Compact Source, Fluorescence Co-registration, Spectral Encoding, Matrix Detection and FRET
<p>Photoacoustic tomography, which detects non-radiative decay, is an emerging biomedical imaging modality that can provide 3D ultrasonically scalable images of biological tissue ranging from organelles to organs. Pure optical imaging modalities (e.g., optical coherence tomography and diffuse …
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Photoacoustic Microscopy and Photoacoustic Computed Tomography Using High-frequency Linear Array Ultrasonic Transducers
<p>Photoacoustic tomography (PAT) is a highly promising imaging technology which forms images by detecting the induced pressure waves resulting from pulsed light absorption in biological tissues. Because the excitation source is light, PAT is a very safe, non-ionizing, and non-carcinogenic imaging …
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Three-Dimensional Photoacoustic Computed Tomography: Imaging Models and Reconstruction Algorithms
<p>Photoacoustic computed tomography: PACT), also known as optoacoustic tomography, is a rapidly emerging imaging modality that holds great promise for a wide range of biomedical imaging applications. Much effort has been devoted to the investigation of imaging physics and the optimization of …
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Image Reconstruction of the Speed of Sound and Initial Pressure Distributions in Ultrasound Computed Tomography and Photoacoustic Computed Tomography
<p>Ultrasound computed tomography (USCT) and photoacoustic computed tomography (PACT) are two emerging imaging modalities that have a wide range of potential applications from pre-clinical small animal imaging to cancer screening in human subjects. USCT is typically employed to measure acoustic …