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Showing 1 to 3 of 3 for “"Photo-cleavable."”.
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Preparation Of Oligonucleotide Delivery Agents And Insulin Depot Materials Using Solid Phase Synthesis
… tethered to a biocompatible depot material. A photo cleavable trigger was used between the insulin and the depot material. Light was used was used to control insulin release. The routes tested for linking the insulin to the depot included a diazo method and an imidazole carbamate method. …
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Development of Tyrosine Kinase Peptide Biosensors and Methods for Detection
… included a biotin-tag for affinity capture, a photo-cleavable amino acid to allow release of the substrate from the delivery module and the cell penetrating peptides TAT. A live cell kinase assay utilizing this biosensor was developed to monitor intercellular Syk activity in response to …
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Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein.
… (and thus their activities). This study utilizes photoconvertible nucleic acid to trigger the biological assembly/disassembly of DNA damage repair proteins on DNA. Specifically, this work focuses on photo-regulation of DNA damage recognition by the xeroderma pigmentosum C complex (XPC-Rad23B; …