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Showing 1 to 4 of 4 for “"Phospholipase C beta"”.
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Dual Regulation of Phospholipase C-beta by G betagamma
… G alpha subunit (Ga), releasing active Ga and G betagamma (Gbg) subunits. Activated alpha subunits of the Gq family and betagamma subunits of the Gi family stimulate phospholipase C-beta (PLC-b) isoforms to catalyze hydrolysis of phosphatidylinositol-1,2-bisphosphate (PIP2) generating the second …
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Phänotypische und molekulare Analyse einer Maus mit Insertionsmutation und axonaler Reorganisation im Hippocampus
… Insertion transgener DNA (TC) in das Phospholipase C-beta 1 -Gen der Maus (PLC-ß1TC-/- -Mutation), die zu einer vollständig penetranten Spleiß-Mutation und zu einem kompletten Verlust von PLC-ß1-Expression führt. PLC-ß1TC-/- -Mäuse zeigen ab einem Alter von 6 Monaten eine auffällige …
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The Role of Arginine Vasopressin Receptor 2 in Microvascular Hyperpermeability During Severe Sepsis and Septic Shock
… increase in permeability is mediated by phospholipase C beta 4 (PLCβ-4) and the potent permeability factor angiopoietin-2. In conclusion, the results of the present work show that endothelial V2R activation increases vascular permeability during sepsis and perhaps its closer modulation …
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Trasduzione del segnale inositide-dipendente nel carcinoma della mammella
… Among the enzymes implicated in this pathway, phospholipase C beta 1 (PLCβ1) is one of the key regulators, both at the cytoplasmic and the nuclear level. The PLCβ1 gene maps onto the short arm of chromosome 20, a region that has been shown to be altered in several solid tumors, including breast …