Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Phosphoglucomutase"”.
-
Phosphoglucomutase 1 (PGM1) expression and regulation in cancer cells
… in cervical cancer patient material. Of these, Phosphoglucomutase 1 (PGM1) was identified to have elevated expression in the cancer group. PGM1 is a phosphotransferase that catalyses the reversible conversion of the glycogen breakdown product, glucose-1-phosphate into glucose-6-phosphate, a …
-
Population Frequencies of Phosphoglucomutase (PGM), Adenylate Kinase (AK), and Haptoglobin (Hp) in the Metropolitan Birmingham Area.
Frequently the need to identify or exclude an individual arises in criminal cases. Historically, fingerprinting has been a universally acceptable method of individual identification. Unfortunately, fingerprints are not always found at the crime scene ; therefore, other methods for identification of …
-
An investigation of proteoforms in health and disease using peptide-level readouts
… Using ten disease-causing mutants of the human phosphoglucomutase 1 (PGM1) protein, we achieved improved resolution using our pooled MS assays compared to previously published studies that relied on individually purified mutants. Scaling of this approach to larger mutant libraries and diverse …
-
The role of glycogen Metabolism in the Adaptation to environmental Changes of the cyanobacterium Synechocystis sp. PCC 6803
… the work identifies the sll0726 as the main phosphoglucomutase. Cellular fitness is compromised under conditions that demand higher flux towards glycogen synthesis, such as high light, nitrogen depletion (chlorosis). This work expands our understanding of how to regulate carbon flow towards …
-
Systematic implications of isozyme number variation in Tribe Brassiceae (Brassicaceae).
… informative. Duplications for cytosolic phosphoglucomutase (Pgm-2) and plastid triosephosphate isomerase (Tpi-1) were evident in 33 of the 35 Brassiceae genera examined, supporting the monophyletic nature of the tribe, with inclusion of Orychophragmus and exclusion of Calepina and …
-
The effects of furosemide on equine skeletal muscle satellite cell myogenesis and metabolism in vitro
… creatine kinase while increasing expression of phosphoglucomutase 1, glycogen synthase 1, and glycogen branching enzyme 1 (P<0.05). Excess furosemide decreased basal oxygen consumption rate (OCR) and increased OCR after addition of oligomycin (P<0.05). Excess furosemide did not affect myotube …
-
Evaluation of Walleye X Sauger Hybrid Introductions in South Dakota Waters
… staining procedures for the supernatant form of phosphoglucomutase (PGM-1). External characteristics did not reliably distinguish walleyes and saugeyes until fishes were 18 cm and longer. I compared walleye and saugeye survival and growth in two turbid impoundments, Lakes Richmond and Mina, and …
-
Molecular Approaches to the Genetics of Obesity: Mapping and Characterization of the Murine Diabetes (db) Gene
… distal to db. Cloning and mapping of the mouse phosphoglucomutase gene established that Pgm-2 is located approximately 1.5 cM proximal of db. Utilizing these flanking markers and genetic resources, pulse-field electrophoresis mapping, and YAC cloning of the region has begun. These studies should …
-
Enzyme-Catalyzed Phosphoryl Transfer Reactions: Energetics of Transition States and Vanadate Analogues in Aqueous Solution
… analogues in the study of DNA Polymerase, β-phosphoglucomutase (β-PGM), and Hexose Phosphate Phosphatase (HPP) -catalyzed phosphoryl transfer reactions. This work seeks to add to the growing body of theoretical work that addresses the cleavage of P-O bonds by offering additional suggestions …
-
Etude de la structure génétique des populations de pétoncle géant (Placopecten Magellanicus) du sud du golfe du St-Laurent par analyse de l'ADNmt et des loci enzymatiques
… isomérase (MPI), octopine déshydrogénase (ODH), phosphoglucomutase (PGM) et isocitrate déshydrogénase (IDH) ont été analyses par focalisation isoélectrique sur gel de polyacrylamide. Les variations alléliques de ces loci, caractérisées par l'expression des isozymes, ont fait l'objet d'une analyse …
-
Etablierung und Charakterisierung einer Tetracyclin-induzierbaren PHD2-Knockdown-HeLa-Zelllinie
… 7 Genen sind 3 Gene hochreguliert (PGM2L1 (phosphoglucomutase 2 like 1), FAP (fibroblast activation protein, alpha) und PTPRE (protein tyrosine phosphatase, receptor type, E)) und 4 Gene herunterreguliert (AES (amino-terminal enhancer of split), RASSF2 (Ras association (RalGDS/AF-6) domain …
-
Targeting final steps of sugar nucleotide biosynthetic pathway against <i>Aspergillus fumigatus</i>
… (UGP). Glc-1-P is synthesized from Glc-6-P by phosphoglucomutase (PGM). Targeting UGP and/or PGM may affect UDP-Glc and therefore elicit antifungal activity. Taken together, these four enzymes are likely to be antifungal targets against A. fumigatus. In this thesis, I will focus on three …